In vivo pharmacology of spleen contraction in ...



Title In vivo pharmacology of spleen contraction in rainbow trout
Author(s) M. Pearson, G. Vanderkraak, E. D. Stevens
Journal Canadian Journal of Zoology / Revue Canadienne De Zoologie
Date 1992
Volume 70
Issue 3
Start page 625
End page 627
Abstract Rainbow trout, Oncorhynchus mykiss, were injected with an adrenergic agonist. an adrenergic antagonist, or a cholinergic antagonist, via a dorsal aorta cannula. Spleen size and haemoglobin content were measured at rest and, for antagonists, following an air exposure stress. Injection of phentolamine (an alpha-antagonist) blocked the spleen contraction induced by air exposure, suggesting that control is mediated by alpha-adrenergic receptors. Air exposure effects were unaffected by beta-adrenergic blockade or muscarinic cholinergic blockade.

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