Synthesis of hydroxyquinoline derivatives, ...
Description
Citation
| Title | Synthesis of hydroxyquinoline derivatives, aminohydroxychromene, aminocoumarin and their antibacterial activities. |
| Author(s) | A. Abd-El-Aziz, A. El-Agrody, A. Bedair, T. Corkery, A. Ata |
| Journal | Section Title: Heterocyclic Compounds (One Hetero Atom), Heterocycles |
| Date | 2004 |
| Volume | 63 |
| Issue | 8 |
| Start page | 1793 |
| End page | 1812 |
| Abstract | Some diaminochromenes, e.g., I, 7-amino-4-aryl-coumarins, 7-hydroxy-4-aryl-1,2-dihydroquinolines, and 2-amino-7-hydroxy-4-(4-chlorophenyl)-4H-chromenes were synthesized via Michael addn. of different substituted aminonaphthol, aminophenol, resorcinol derivs., chloronaphthol, and 4-hydroxycoumarin with α-cyanocinnamonitriles and Et α-cyanocinnamates. 2-Acetylamino-7-amino-4-(4-chlorophenyl)-4H-chromene-2-carbonitrile was obtained as a unique product via hydrazinolysis of the corresponding ethoxymethyleneamino deriv. The formation of coumarins and quinolines were anomalous case. Structures of the titled compds. were elucidated by spectrometric data; IR, 1H NMR, 13C NMR (APT), and EMS. All of the synthesized compds. were evaluated for antimicrobial activities, and some of the compds. exhibited activity against staphylococcus aureus (ATCC 25923). [on SciFinder(R)] |
| ISSN | 0385-5414 |
Using APA 6th Edition citation style.
[Page generation failure. The bibliography processor requires a browser with Javascript enabled.]
Times viewed: 82
