Reductions in paradoxical sleep time in adult rats ...

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Title Reductions in paradoxical sleep time in adult rats treated neonatally with low dose domoic acid
Author(s) D. A. Gill, J. F. Bastlund, N. J. Anderson, R. A. Tasker
Journal Behavioural Brain Research
Date 2009
Volume 205
Issue 2
Start page 564
End page 567
Abstract One hallmark of neurological dysfunction is a reduction in paradoxical sleep (PS) time. To determine if adult rats treated neonatally with low dose domoic acid have altered sleep patterns, a home cage analysis of electroencephalogram (EEG) waveforms was performed using radio telemetry. Domoate treated rats spent significantly less time in PS than controls during daytime hours even though they spent the same total amount of time sleeping, and showed no difference in stage shifts into the PS stage.
DOI 10.1016/j.bbr.2009.07.018

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