Arginine vasopressin in hypothalamic paraventricular ...

Description

Citation

Title Arginine vasopressin in hypothalamic paraventricular nucleus is transferred to the nucleus raphe magnus to participate in pain modulation
Author(s) Jun Yang, Huifeng Yuan, Wenyan Liu, Chaoyou Song, Hongtao Xu, Gen Wang, Cai Song, Na Ni, Daiwei Yang, Baocheng Lin
Journal Peptides
Date 2009
Volume 30
Issue 9
Start page 1679
End page 1682
Abstract Hypothalamic paraventricular nucleus (PVN) is one of the main sources of arginine vasopressin (AVP) synthesis and secretion. AVP is the most important bioactive substance in PVN regulating pain process. Our pervious study has pointed that pain stimulation induced AVP increase in the nucleus raphe magnus (NRM), which plays a role in pain modulation. The present study was designed to investigate the source of AVP in the rat NRM during pain process using the methods of nucleus push–pull perfusion and radioimmunoassay. The results showed that pain stimulation increased the AVP concentration in the NRM perfusion liquid, PVN cauterization inhibited the role that pain stimulation induced the increase of AVP concentration in the NRM perfusion liquid, and PVN microinjection of l-glutamate sodium, which excited the PVN neurons, could increase the AVP concentration in the NRM perfusion liquid. The data suggested that AVP in the PVN might be transferred to the NRM to participate in pain modulation.
DOI 10.1016/j.peptides.2009.05.026

Using APA 6th Edition citation style.

[Page generation failure. The bibliography processor requires a browser with Javascript enabled.]

Times viewed: 215

Adding this citation to "My List" will allow you to export this citation in other styles.