|Building||Irving Chemistry Centre 213|
BSc, University of Prince Edward Island (1988); PhD, McGill University, Montréal (1995); PDF, University of California at Santa Barbara, (1996-2000)
Dr. Barry Linkletter works to better understand and synthesize molecules that will interact and associate with four-stranded DNA, a novel DNA structure. These stabilizing molecules are candidates for drugs that regulate cell proliferation and may find a use in cancer therapy and genetic research.
- Rapid hydrolysis of 2 ',3 '-cAMP with a Cu(II) complex
- Solid-phase synthesis of deoxynucleic guanidine (DNG) oligomers and melting point and circular dichroism analysis of binding fidelity of octameric thymidyl oligomers with DNA oligomers
- Synthesis of protected guanidinium linked dinucleoside incorporable into an oligonucleotide using solid phase DNA methodology
- Rapid hydrolysis of RNA with a CU-II complex
- Benzylchlorocarbene: UV absorption spectrum, kinetics for 1,2-H migration and mechanism for reaction with acetic acid as determined by combined continuous and laser-flash photolysis