Low dose domoic acid in neonatal rats abolishes ...
Description
Citation
| Title | Low dose domoic acid in neonatal rats abolishes nicotine induced conditioned place preference during late adolescence |
| Author(s) | M. Burt, C. Ryan, T. Doucette |
| Journal | Amino Acids |
| Date | 2008 |
| Volume | 35 |
| Issue | 1 |
| Start page | 247 |
| End page | 249 |
| Abstract | In this study, neonatal rats were chronically exposed to low, non-convulsive doses of the kainate receptor agonist domoic acid (DOM), or saline. Later, as adolescents, all animals were tested in a nicotine-induced conditioned place preference (CPP) paradigm. As expected, a nicotine-induced CPP was evident in the adolescent control rats, but surprisingly, not in the DOM animals. This study demonstrates the importance of KA receptors in the development of normal adolescent behaviors manifested in response to the rewarding properties of nicotine. |
| ISSN | 1438-2199 |
Using APA 6th Edition citation style.
[Page generation failure. The bibliography processor requires a browser with Javascript enabled.]
Times viewed: 94
