Tracheal versus pulmonary deposition and clearance ...
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Citation
| Title | Tracheal versus pulmonary deposition and clearance of inhaled Pasteurella haemolytica or Staphylococcus aureus in mice |
| Author(s) | L. Rodriguez, A. Lopez |
| Journal | Canadian Journal of Comparative Medicine |
| Date | 1985 |
| Volume | 49 |
| Issue | 3 |
| Start page | 323 |
| End page | 326 |
| Abstract | The aim of this investigation was to do a comparative study on the deposition and clearance of inhaled bacteria between the lungs and tracheae of mice exposed to aerosols of bacteria. Mice were divided into 4 groups of 72 each and exposed to aerosols of P. haemolytica or S. aureus in 4 replicates. The numbers of bacteria were determined in the trachea and lungs of mice sacrificed 0, 2, 4, 8 12, 24, 48 and 72 h postexposure. Results indicated that bacterial deposition was greater in lungs than in tracheae. No significant (P > 0.05) difference was observed between P. haemolytica and S. aureus clearance rates. Although bacteria were rapidly eliminated from the whole respiratory tract, bacterial clearance was significantly (P < 0.002) faster in tracheae than lungs. A significant (P < 0.05) replicate effect was also observed. |
| ISSN | 0008-4050 ER |
Using APA 6th Edition citation style.
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