Synthesis of alpha-amino-acids by addition of ...

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Title Synthesis of alpha-amino-acids by addition of putative azido radicals to alpha-methoxy acrylonitriles derived from aldehydes and ketones
Author(s) D. Clive, N. Etkin
Journal Tetrahedron Letters
Date 1994
Volume 35
Issue 16
Start page 2459
End page 2462
Abstract alpha-Methoxy acrylonitriles, available from aldehydes and ketones, react with sodium azide in the presence of eerie ammonium nitrate to give azido nitrates; from these compounds, alpha-amino acids are obtained by sequential treatment with sodium acetate in acetic acid and then methanolic potassium carbonate, followed by hydrogenation.
ISSN 0040-4039

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