Changes in smooth muscle contractility of rainbow ...
|Title||Changes in smooth muscle contractility of rainbow trout (Oncorhynchus mykiss Walbaum) intestine during acclimation to altered temperature|
|Author(s)||John F. Burka, H. A. Briand, L. M. Purcell, G. A. Mitton, J. G. Hogan, W. P. Ireland|
|Journal||Fish Physiology and Biochemistry|
|Abstract||The effects of altered water temperature in vivo on in vitro smooth muscle contractility of rainbow trout intestine were investigated. Temperature has a significant effect on receptor-mediated intestinal smooth muscle contractility in the rainbow trout. The efficacy of 5-HT, carbachol, and transmural stimulation increased with temperatures above 10-degrees-C, with an optimal increase at 15-degrees-C. There was also a modest increase in the potency of 5-HT and carbachol within 2 days of establishing trout at 20-degrees-C. By day 8, most of these changes had either stabilized or were returning to control values, suggesting that acclimation changes in membranes and enzyme activities were taking effect. However, the contractile responses to carbachol and transmural stimulation were still increasing at this time. This may imply that the muscarinic receptors are more resistant to membrane acclimation changes and may take longer to adapt. Because these experiments were controlled for handling stress and seasonal changes that affect contractility, we have been able to demonstrate some early changes in smooth muscle contractility that occur during acclimation to altered temperature.|
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