Excretion of intra-uterine applied oxytetracycline ...

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Title Excretion of intra-uterine applied oxytetracycline and lugol in cows milk
Author(s) T. Dijkstra, H. W. Barkema, R. D. Vanbuuren, J. G. Vanspanje, H. Jorritsma
Journal Tijdschrift voor Diergeneeskunde
Date 1994
Volume 119
Issue 21
Start page 634
End page 636
Abstract Sixteen dairy cows with chronic puerperal endometritis between 3 and 8 weeks post partum were treated with intra-uterine applied oxytetracycline (OTC) and lugol. OTC was rapidly removed from plasma and was not detectable after 48 hours. The concentration of OTC in milk did not exceed 40 mu g/kg, and it was still detectable in milk 34 hours after treatment. The concentration of OTC in milk was always lower than the limit of 50 mu g/kg used by milk-testing stations and the European limit (MRL) of 100 mu g/kg. Milk from cows treated with lugol did nor cause inhibition in the plate test.

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