Use of 111In-labeled autologous leukocytes to image ...

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Title Use of 111In-labeled autologous leukocytes to image an abdominal abscess in a horse
Author(s) P. D. Koblik, Jeanne Lofstedt, R. M. Jakowski, K. L. Johnson
Journal Journal of the American Veterinary Medical Association
Date 1985
Volume 186
Issue 12
Start page 1319
End page 1322
Abstract Indium 111-labeled autologous leukocytes were used to image an abdominal abscess in a horse with a palpable abdominal mass and history of Streptococcus equi infection. A focal area of radioactivity was identified in the location corresponding to the abscess. Imaging of this focal uptake was optimal 48 hours after injection. Similar scans obtained in 2 clinically normal horses revealed no evidence of focal radioactivity in this region. The cell labeling procedure gave acceptable labeling efficiency (87.5%) but an excessive number of damaged WBC, resulting in persistent lung radioactivity on all images. No adverse effects were noted. Radiation measured in the horse and its excreta were well within acceptable limits.

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