Gastric conduit urinary diversion in normal dogs. ...

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Title Gastric conduit urinary diversion in normal dogs. Part II, Hypochloremic metabolic alkalosis
Author(s) M. A. McLoughlin, R. Walshaw, M. W. Thomas, J. G. Hauptman
Journal Veterinary Surgery: VS: The Official Journal of the American College of Veterinary Surgeons
Date 1992
Volume 21
Issue 1
Start page 33
End page 39
Abstract Gastric conduit urinary diversion was performed in 10 dogs after complete cystectomy. Four dogs were euthanatized on day 30 because of hypochloremic metabolic alkalosis and renal failure. Hematologic and biochemical changes in six dogs evaluated for 120 days were compatible with hypochloremic metabolic alkalosis. The continuous loss of hydrochloric acid from the gastric conduit resulted in significant increases in arterial blood pH, PaCO2, anion gap, TCO2, and the concentration of HCO3-. There were significant decreases in PaO2 and the serum concentrations of chloride and potassium. Deterioration of renal function resulted in all dogs. It was concluded that hypochloremic metabolic alkalosis makes gastric conduit urinary diversion unsatisfactory for clinical use in dogs.

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