A microbiological assay for determining sarafloxacin ...



Title A microbiological assay for determining sarafloxacin and oxolinic acid concentrations in Atlantic salmon plasma
Author(s) J. S. Giles, H. Hariharan, S. B. Heaney
Journal The New Microbiologica: Official Journal of the Italian Society for Medical, Odontoiatric, and Clinical Microbiology (SIMMOC)
Date 1994
Volume 17
Issue 2
Start page 155
End page 158
Abstract A microbiological assay was developed to quantify the concentrations of the quinolone antibiotics sarafloxacin and oxolinic acid in Atlantic salmon (Salmo salar) plasma. The assay was a modification of the Association of Official Analytical Chemists (AOAC) method for antibiotic concentrations in feeds using disk diffusion and a lawn of Vibrio anguillarum ATCC 19264 as the test organism. With these modifications, sensitivities of 0.04 microgram/mL for sarafloxacin and 0.125 micrograms/mL for oxolinic acid were obtained.

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