Ofloxacin susceptibilities of 5,667 Neisseria ...
|Title||Ofloxacin susceptibilities of 5,667 Neisseria gonorrhoeae strains isolated in Hong Kong|
|Author(s)||K. M. Kam, K. K. Lo, C. F. Lai, Y. S. Lee, Catherine B. Chan|
|Journal||Antimicrobial Agents and Chemotherapy|
|Abstract||Of 5,667 strains of Neisseria gonorrhoeae isolated from the Government Social Hygiene (sexually transmitted disease) Clinics in Hong Kong from 1990 to 1992, there was a trend toward an increase in the percentage of strains resistant in vitro to 0.01 and 0.1 microgram of ofloxacin per ml, with 54.3 and 5.5% resistant strains, respectively, in January 1990, rising to 95.3 and 41.5%, respectively, in December 1992. The percentage of strains for which the MIC is > 1 microgram/ml remains stable, and no clinical failure has yet been seen. This trend of decreasing susceptibility warrants close monitoring when ofloxacin is used as first-line treatment for gonorrhea.|
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