Release of immunosuppressive substances from tissue ...



Title Release of immunosuppressive substances from tissue culture cells infected with bovine viral diarrhea virus
Author(s) R. J. Frederick Markham, M. L. Ramnaraine
Journal American Journal of Veterinary Research
Date 1985
Volume 46
Issue 4
Start page 879
End page 883
Abstract Bovine fetal lung tissue culture cells were infected with bovine viral diarrhea virus. The cells released substances into the supernatant fluid that suppressed the proliferative response of bovine peripheral blood mononuclear cells which had been stimulated with concanavalin A. Activity could be found in low molecular weight fractions (less than or equal to 2,000 daltons). During the assay, these fractions were required to inhibit the response of leukocytes to concanavalin A. Addition of indomethacin to the infected tissue culture cells inhibited generation of immunosuppressive supernatants; addition of indomethacin to the suppressive supernatants did not block their activity. The possible involvement of prostaglandins in this immunosuppressive activity is discussed.

Using APA 6th Edition citation style.

[Page generation failure. The bibliography processor requires a browser with Javascript enabled.]

Times viewed: 428

Adding this citation to "My List" will allow you to export this citation in other styles.