Virulence and pathogenicity of infectious salmon ...

Description

Citation

Title Virulence and pathogenicity of infectious salmon anemia virus isolated from farmed salmon in Atlantic Canada
Author(s) S. R. M. Jones, A. M. MacKinnon, David B. Groman
Journal Journal of Aquatic Animal Health
Date 1999
Volume 11
Issue 4
Start page 400
End page 405
Abstract Infectious salmon anaemia virus (ISAV) was isolated from farmed Atlantic salmon (Salmo salar) associated with an outbreak of haemorrhagic kidney syndrome in the Bay of Fundy, Canada. The virus induced cytopathic effects in salmon head kidney cell line SHK-1 from Atlantic salmon and was positively confirmed as ISAV by an indirect fluorescent antibody test and by reverse transcriptase polymerase chain reaction. Atlantic salmon parr injected with ISAV from the SHK-1 line experienced significant reductions in haematocrits as early as 5 days postinfection (DPI). Mortality began 17 DPI and reached 76% by 24 DPI at a water temperature of 11 degrees C. In a second trial, similarly high mortality occurred in salmon parr injected with 10-fold dilutions of supernatant from ISAV-infected SHK-1 cultures. The ISAV was reisolated from 8 randomly selected salmon that died after experimental infection. Microscopic pathological changes among infected fish included congestion and necrosis, seen in the livers from 7 of 19 samples and in the kidney from 1 of 18 salmon examined. Other tissues affected included gill, intestine, and pyloric caeca. The absence of microscopic lesions in the remaining experimentally infected fish could not be explained..
DOI 10.1577/1548-8667(1999)011<0400:VAPOIS>2.0.CO,2
Use/Reproduction Contact Publisher
Text http://www.islandscholar.ca/download_ds/ir%3Air-batch6-3824/PDF/ir_ir-batch6-3824.pdf

Using APA 6th Edition citation style.

[Page generation failure. The bibliography processor requires a browser with Javascript enabled.]

Times viewed: 286

Adding this citation to "My List" will allow you to export this citation in other styles.