Evaluation of six antimicrobial agents against fish ...

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Title Evaluation of six antimicrobial agents against fish pathogenic isolates of Vibrio anguillarum, Vibrio ordalii and Aeromonas salmonicida
Author(s) J. S. Giles, H. Hariharan, S. B. Heany
Journal Bulletin of the Aquaculture Association of Canada
Date 1991
Volume
Issue 3
Start page 53
End page 55
Abstract The minimum inhibitory concentrations (MICs) of six antimicrobial agents were determined for Atlantic coast isolates of V. anguillarum, V. ordalii and A. salmonicida collected between 1985 and 1990. MIC values were calculated by agar dilution at 3 incubation temperatures (10, 20, 30 degrees C) for the following: oxytetracycline, Romet-30 (5:1 sulfadimethoxine + ormetoprim), oxolinic acid, sarafloxacin, erythromycin and streptomycin. MICs for oxytetracycline against V. anguillarum and V. ordalii showed a 2-fold increase as incubation temperature increased. This pattern was not seen for A. salmonicida, although the frequency of resistant strains was greater. Vibrio isolates were more sensitive to sarafloxacin, oxolinic acid and Romet-30 (MIC50 0.0156-0.25 micro g/ml) than A. salmonicida (MIC50 0.03-4 micro g/ml), but were more resistant to streptomycin (32 micro g/ml) and erythromycin (16 micro g/ml) than A. salmonicida (8 micro g/ml)..

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