lin-31, a Caenorhabditis elegans HNF-3/fork head ...
|Title||lin-31, a Caenorhabditis elegans HNF-3/fork head transcription factor homolog, specifies three alternative cell fates in vulva development|
|Author(s)||Lisa M. Miller, M. E. Gallegos, B. A. Morisseau, S. K. Kim|
|Journal||Genes and Development|
|Abstract||Late events in the cell-cell signalling pathway that controls the specification of vulva cell fates in C. elegans are characterized. The lin-31 gene acts downstream of the ras homolog let-60 and encodes a member of the HNF-3/fork head family of DNA-binding transcription factors. lin-31 regulates how vulval precursor cells choose their fate and in lin-31 mutants, these cells do not properly choose which fate to express and therefore adopt any of the 3 possible vulval cell fates in a deregulated manner..|
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