Inheritance of congenital myasthenia gravis in ...



Title Inheritance of congenital myasthenia gravis in smooth fox terrier dogs
Author(s) Lisa M. Miller, G. A. Hegreberg, D. J. Prieur, M. J. Hamilton
Journal Journal of Heredity
Date 1984
Volume 75
Issue 3
Start page 163
End page 166
Abstract The phenotypes with respect to congenital myasthenia gravis of 132 Smooth Fox Terrier dogs from 25 matings were analysed. These included both prospective and retrospective matings. It was determined that congenital myasthenia gravis in this breed is inherited in an autosomal recessive manner with complete penetrance. The symbol mg is proposed for the gene for congenital myasthenia gravis in the smooth fox terrier. Attempts to maintain live affected dogs to adulthood were unsuccessful and it is concluded that this is a lethal trait..

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