Experimental vaccination of rainbow trout against ...
|Title||Experimental vaccination of rainbow trout against Loma salmonae using a live low-virulence variant of L. salmonae|
|Author(s)||J. G. Sanchez, David J. Speare, R. J. Frederick Markham, S. R. M. Jones|
|Journal||Journal of Fish Biology|
|Abstract||The induction of protection against xenoma development by vaccinated (previously exposed to a low-virulence strain of Loma salmonae; n=40) and naive (n=40) rainbow trout (Oncorhynchus mykiss) challenged with the virulent typical strain of L. salmonae, was determined. Prevalence of infection was lower in vaccinated rainbow trout than in the naive fish. Fish that have been vaccinated with L. salmonae SV spores showed significantly lower numbers of xenomas per filament (P<=0.05), from 3 to 6 weeks post exposure (PE). At the peak of the disease, 4 and 6 weeks PE, vaccinated fish had 14 times fewer xenomas than the naive fish (P=0.0001). A single exposure to L. salmonae SV induced protection from disease in juvenile rainbow trout when challenged 15 weeks later with typical, virulent spores..|
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