Gastrinoma (Zollinger-Ellison syndrome) in the dog ...



Title Gastrinoma (Zollinger-Ellison syndrome) in the dog and cat
Author(s) Darcy H. Shaw
Journal Canadian Veterinary Journal
Date 1988
Volume 29
Issue 5
Start page 448
End page 452
Abstract Tumours of gastrin-secreting cells (gastinomas) which result in a characteristic clinical syndrome of hypergastinaemia, leading to gastric acid hypersecretion with subsequent severe gastrointestinal ulceration are reviewed. The most common clinical signs are anorexia, lethargy, weight loss, vomiting, diarrhoea, and hypoalbuminaemia. Hypergastrinaemia is also seen in other disorders and caution should be used in utilizing fasting serum gastrin concentrations as the sole diagnostic criterion..

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