Test characteristics from latent-class models of the ...



Title Test characteristics from latent-class models of the California Mastitis Test
Author(s) C. J. Sanford, Gregory P. Keefe, J. Sanchez, R. T. Dingwell, H. W. Barkema, K. E. Leslie, Ian R. Dohoo
Journal Preventive Veterinary Medicine
Date 2006
Volume 77
Issue 1-2
Start page 96
End page 108
Abstract We evaluated (using latent-class models) the ability of the California Mastitis Test (CMT) to identify cows with intramammary infections on the day of dry-off. The positive and negative predictive values of this test to identify cows requiring dry-cow antibiotics (i.e. infected) was also assessed. We used 752 Holstein-Friesian cows from 11 herds for this investigation. Milk samples were collected for bacteriology, and the CMT was performed cow-side, prior to milking on the day of dry-off. At the cow-level, the sensitivity and specificity of the CMT (using the four quarter results interpreted in parallel) for identifying all pathogens were estimated at 70 and 48%, respectively. If only major pathogens were considered the sensitivity of the CMT increased to 86%. The negative predictive value of the CMT was >95% for herds with major-pathogen intramammary-infection prevalence <15%, so that selective dry-cow therapy might be reasonable for such herds if cows were screened with the CMT.
DOI 10.1016/j.prevetmed.2006.06.006

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