Ethyl-eicosapentaenoic acid ingestion prevents ...

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Title Ethyl-eicosapentaenoic acid ingestion prevents corticosterone-mediated memory impairment induced by central administration of interleukin-1? in rats
Author(s) C. Song, A. G. Phillips, B. E. Leonard, D. F. Horrobin
Journal Molecular Psychiatry
Date 2004
Volume 9
Issue 6
Start page 630
End page 638
Abstract Central or peripheral administration of the proinflammatory cytokine interleukin (IL)-1? can impair performance on spatial memory tasks and also elevate circulating concentration of corticosterone. The present experiment provides independent confirmation that intracerebroventricular administration of 10ng IL-1? in the rat can have a selective effect on the retrieval of trial unique information about the location of food on an eight-arm radial maze.
DOI 10.1038/sj.mp.4001462

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