In vitro immunoregulatory effects of lithium in ...



Title In vitro immunoregulatory effects of lithium in healthy volunteers
Author(s) Michael Maes, Cai Song, Ai-hua Lin, Rosaria Pioli, Gunter Kenis, Marta Kubera, Eugene Bosmans
Journal Psychopharmacology
Date 1999
Volume 143
Issue 4
Start page 401
End page 407
Abstract Examined the in vitro effects of lithium carbonate on the unstimulated and lipolysaccharide (LPS)?+?phytohemagglutinin (PHA)-induced production of proinflammatory cytokines, such as interleukin-6 (IL-6), IL-8, tumor necrosis factor-? (TNF?) and interferon-? (IFN?), and negative immunoregulatory cytokines or proteins, such as IL-10 and the IL-1 receptor antagonist (IL-1RA).

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