David Sims

Description

Details

NameDavid Sims
PositionFaculty Member
Emailsims@upei.ca
Department(s)Biomedical Sciences
Phone(902) 566-0812
BuildingAVC 2320A
Websitehttp://www.upei.ca/avc/david-sims

Research Interests

  • Generally, the structure and function of blood vessels, particularly small vessels and their alterations during inflammation
  • Specifically, the inner glycocalyx, pericytes, endothelial cells and the connective tissues of blood vessels, which are affected by inflammation and other challenges

Other Scholars in Biomedical Sciences

Citations

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TitleAuthor(s)
Efficacy of levamisole and netobimin against Haemonchus contortus in lambs in LouisianaMiller, J. E.; Hembry, F. G.; Kearney, M. T.; Williams, J. C.; Stagg, L. C.; Sims, D. E.
Efficacy of repeated doses of levamisole, morantel, fenbendazole, and ivermectin against gastrointestinal nematodes in ewesHembry, F. G.; Miller, J. E.; Sims, D. E.; Rodriguez, S.; Stagg, L. C.
Follicular cysts in sheepOz, H. H.; Foil, C. S.; Memon, M. A.; Al-Bagdadi, F. K.; Turk, M. A.; Sims, D. E.
Polarity of pericytes on ileal villous capillariesSims, David E.; Horne, M. M.; Baldwin, A.
Closed e-mail lists improve class communicationsSims, David E.; Singh, A.; Cairns, D.
Non-aqueous fixative preserves macromolecules on the endothelial cell surfaceSims, David E.; Horne, M. M.
Erythrophagocytosis in the caprine hemal nodeEzeasor, D. N.; Singh, A.; Sims, David E.
Interleukin-10 inhibits interleukin-2-induced tumor necrosis factor production but does not reduce toxicity in mice.Lentsch, A. B.; Edwards, M. J.; Sims, David E.; Nakagawa, K.; Miller, F. N.
Erythrocyte dyscrasia, anemia, and hypothyroidism in chronically underweight llamasSmith, B. B.; Reed, P. J.; Pearson, E. G.; Long, P.; Lassen, E. D.; Watrous, B. J.; Lovelady, S.; Sims, David E.; Snyder, S. P.
Ultrastructure of pericytes in early stages of histamine-induced inflammationSims, David E.; Miller, F. N.; Donald, A.; Perricone, M. A.
Preliminary ultrastructural studies of the surface mucus of Atlantic salmonHorne, M. M.; Sims, David E.
Mechanisms of interleukin-2-induced hepatic toxicityNakagawa, K.; Miller, F. N.; Sims, David E.; Lentsch, A. B.; Miyazaki, M.; Edwards, M. J.
Analysis of relationships between pericytes and gas exchange capillaries in neonatal and mature bovine lungsSims, David E.; Westfall, J. A.
Contractile elements in the regulation of macromolecular permeabilityMiller, F. N.; Sims, David E.
Linking the basic sciences in teaching: suggestions for histology instructionSims, David E.; Singh, A.; Amend, J.
Heterogeneity of the composition and thickness of tracheal mucus in ratsSims, David E.; Horne, M. M.
The ultrastructure of nitzschia pungens f multiseries grun ex hasleMacphee, D.; Friesen, D.; Hanic, Louis A.; Sims, David E.
Liver ultrastructure from the rat fed PCB 28.Singh, A.; Sims, David E.; Chu, I.; Villeneuve, D. C.
Limitations of monastral blue as a vascular labelDrake, W. T.; Creighan, M.; Sims, David E.
Recent advances in pericyte biology: implications for health and diseaseSims, David E.
Non-aqueous fixative preserves macromolecules on the endothelial cell surfaceSims, David E.; Horne, M. M.
A role of pericytes in skeletal-muscle vasculature during macromolecular leakageSims, David E.; Miller, F. N.; Perricone, M.
Interleukin-2 alters the positions of capillary and venule pericytes in rat cremaster muscleSims, David E.; Miller, F. N.; Horne, M. M.; Edwards, M. J.
Interleukin-10 inhibits interleukin-2-induced tumor necrosis factor production but does not reduce toxicity in C3H/HeN miceLentsch, A. B.; Edwards, M. J.; Sims, David E.; Nakagawa, K.; Wellhausen, S. R.; Miller, F. N.
Morphometric analysis of pericyte-gas exchange capillary relationships in neonatal and mature bovine lungsSims, David E.; Westfall, J. A.
The effect of soluble tumor necrosis factor receptor-II on endotoxin-mediated hemodynamic instabilityAnderson, J. A.; Knott, A. W.; Wilson, M. A.; Garrison, R. N.; Sims, David E.; Edwards, M. J.
Ultrastructure of fibroblasts and pericytes in the parenchyma of neonatal and mature bovine lungsSims, David E.
Orientation of adhering junctions between bovine pulmonary fibroblastsSims, David E.
Pericytes and endothelial cell-junctions of bovine gas-exchange capillaries are concentrated where the blood-air barrier is thickestSims, David E.; Westfall, J. A.
Microfilament-associated adhering junctions (6 nm F-maculae adherentes) connect bovine pulmonary fibroblasts in vivoSims, David E.; Westfall, J. A.
Tumor necrosis factor causes microvascular protein leakage independently of neutrophils or mast cellsAnderson, J. A.; Miller, F. N.; Sims, David E.; Edwards, M. J.
N omega-nitro-L-arginine methyl ester inhibits inflammatory liver injury induced by interleukin-2Lentsch, A. B.; Edwards, M. J.; Sims, David E.; Miller, F. N.
Differentiation of light-dye effects in the microcirculationMiller, F. N.; Sims, David E.; Schuschke, D. A.; Abney, D. L.
Matrix metalloproteinase-2 (MMP-2) is present in the nucleus of cardiac myocytes and is capable of cleaving poly (ADP-ribose) polymerase (PARP) in vitroKwan, J. A.; Schulze, C. J.; Wang, W.; Leon, H.; Sariahmetoglu, M.; Sung, M.; Sawicka, J.; Sims, David E.; Sawicki, G.; Schulz, R.
Neuro-epitheliomuscular cell and neuro-neuronal gap junctions in hydraWestfall, J. A.; Kinnamon, J. C.; Sims, David E.
Alteration of primate ovary surface epithelium by exposure to hexachlorobenzeneSims, David E.; Singh, A.; Donald, A.; Jarrell, J.; Villeneuve, D. C.
Preservation of tracheal mucus by nonaqueous fixativeSims, David E.; Westfall, J. A.; Kiorpes, A. L.; Horne, M. M.
Junctions connecting microfilament bundles between bovine pulmonary fibroblastsSims, David E.; Westfall, J. A.
The pericyte: a reviewSims, David E.
Comparative morphology of the scolices and microtriches among five species of Tetrabothrius (EucestodaHoberg, E. P.; Sims, David E.; Odense, P. H.
Interleukin 2 acutely induces platelet and neutrophil-endothelial adherence and macromolecular leakageEdwards, M. J.; Miller, F. N.; Sims, David E.; Abney, D. L.; Schuschke, D. A.; Corey, T. S.
Diversity within pericytesSims, David E.
The first experience of livestock guarding dogs preventing large carnivore damages in FinlandOtstavel, Teet; Vuoric, Kristiina A.; Sims, David E.; Valros, Anna; Vainio, Outi; Saloniemi, Hannu
Heterogeneity of pericyte populations in equine skeletal muscle and dermal microvesselsSims, D. E.; Horne, M. M.; Creighan, M.; Donald, A.
Adaptation of a fluorocarbon-based non-aqueous fixation regime for the ultrastructural study of the teleost epithelial mucous coatSanchez, J. G.; Speare, David J.; Sims, David E.; Johnson, G. J.
Uptake, disposition and depuration of domoic acid by blue mussels (Mytilus edulis)Novaczek, Irene; Madhyastha, M. S.; Ablett, R. F.; Johnson, Gerald R.; Nijjar, M. S.; Sims, David E.
Distribution of Crenosoma vulpis and Eucoleus aerophilus in the lung of free-ranging red foxes (Vulpes vulpes)Nevarez, A.; Lopez, Alfonso; Conboy, Gary A.; Ireland, W.; Sims, David E.
Skin morphology and humoral non-specific defence parameters of mucus and plasma in rainbow trout, coho and Atlantic salmonFast, M. D.; Sims, David E.; Burka, John F.; Mustafa, A.; Ross, N. W.
Invitro study of domoic acid uptake by digestive gland tissue of blue mussel (Mytilus-edulis-L)Madhyastha, M. S.; Novaczek, Irene; Ablett, R. F.; Johnson, Gerald R.; Nijjar, M. S.; Sims, David E.
A comparative study of uptake and release of glutamic acid and kainic acid by blue mussel (Mytilus edulis L.)Madhyastha, M. S.; Novaczek, Irene; Ablett, R. F.; Johnson, Gerald R.; Nijjar, M. S.; Sims, David E.
Effect of emu oil on auricular inflammation induced with croton oil in miceLopez, Alfonso; Sims, David E.; Ablett, R. F.; Skinner, R. E.; Leger, L. W.; Lariviere, C. M.; Jamieson, L. A.; Martinez-Burnes, J.; Zawadzka, G. G.
Morphology of the toxin-producing diatom Nitzschia-pungens Grunow forma multiseries HasleMacphee, D. J.; Hanic, Louis A.; Friesen, D. L.; Sims, David E.
In vitro study of domoic acid uptake by digestive gland tissue of blue mussel (Mytilus edulis L.)Madhyastha, M. S.; Novaczek, Irene; Ablett, R. F.; Johnson, Gerald R.; Nijjar, M. S.; Sims, David E.
Morphometric assessment of epidermal and mucous-biofilm changes caused by exposure of trout to chloramine-T or formalin treatmentSanchez, J. G.; Speare, David J.; Sims, David E.; Johnson, G. J.
Depuration of domoic acid from live blue mussels (Mytilus edulis )Novaczek, Irene; Madhyastha, M. S.; Ablett, R. F.; Donald, A.; Johnson, Gerald R.; Nijjar, M. S.; Sims, David E.
Liver ultrastructure from the rat fed BCB 28.Singh, A.; Sims, D. E.; Chu, I.; Villeneuve, D. C.
Techniques for preservation of extracellular mucus - evaluation with the diatom Nitzschia pungens and rat tracheal epitheliumSims, David E.; Hanic, Louis A.; Connell, B. J.; Novaczek, Irene; Ablett, R.; Nijjar, M. S.; Johnson, Gerald R.; Horne, M.
The physiological response of Atlantic salmon, Salmo salar L., to a single experimental challenge with sea lice, Lepeophtheirus salmonisBowers, J. M.; Mustafa, A.; Speare, David J.; Conboy, Gary A.; Brimacombe, M.; Sims, David E.; Burka, John F.
Estimation of total glomerular number using an integrated disector method in embryonic and postnatal kidneysArsenault, Michel; Miao, Yuan ; Jones, Kathleen; Sims, David ; Spears, Jonathan ; Wright, Glenda M ; Hartwig, Sunny
Susceptibility of rainbow trout Oncorhynchus mykiss, Atlantic salmon Salmo salar and coho salmon Oncorhynchus kisutch to experimental infection with sea lice Lepeophtheirus salmonisFast, M. D.; Ross, N. W.; Mustafa, A.; Sims, David E.; Johnson, S. C.; Conboy, Gary A.; Speare, David J.; Johnson, Gerald R.; Burka, John F.
The transcription factor sry-related HMG box-4 (SOX4) is required for normal renal development in vivoHuang, Jez; Arsenault, Michel; Kann, Martin; Lopez-Mendez, Carlos; Saleh, Monique; Wadowska, Dorota; Tahlienti, Mary; Ho, Jacqueline; Miao, Yuan; Sims, David; Spears, Jonathan; Lopez, Alfonso; Wright, Glenda; Hartwig, Sunny
Physiological, biochemical, and histological approaches to examining sea lice-salmon interactionsBurka, John F.; Conboy, Gary A.; Sims, David E.; Speare, David J.; Mustafa, A.; Ross, N. W.

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TitleTimes viewedLast viewed
Efficacy of levamisole and netobimin against Haemonchus contortus in lambs in Louisiana - ir:452724613:41:39 2015-08-25
Efficacy of repeated doses of levamisole, morantel, fenbendazole, and ivermectin against gastrointestinal nematodes in ewes - ir:450026821:43:39 2015-08-25
Follicular cysts in sheep - ir:453625721:50:46 2015-09-02
Polarity of pericytes on ileal villous capillaries - ir:ir-batch6-51237306:22:13 2015-09-02
Closed e-mail lists improve class communications - ir:ir-batch6-51441008:01:55 2015-09-02
Non-aqueous fixative preserves macromolecules on the endothelial cell surface - ir:ir-batch6-49440905:59:41 2015-09-03
Erythrophagocytosis in the caprine hemal node - ir:ir-batch6-50534110:36:21 2015-09-03
Interleukin-10 inhibits interleukin-2-induced tumor necrosis factor production but does not reduce toxicity in mice. - ir:ir-batch6-51536021:06:00 2015-09-02
Erythrocyte dyscrasia, anemia, and hypothyroidism in chronically underweight llamas - ir:ir-batch6-50139609:32:28 2015-09-01
Ultrastructure of pericytes in early stages of histamine-induced inflammation - ir:ir-batch6-50438117:17:15 2015-08-31
Preliminary ultrastructural studies of the surface mucus of Atlantic salmon - ir:ir-batch6-52543019:46:13 2015-09-02
Mechanisms of interleukin-2-induced hepatic toxicity - ir:ir-batch6-48835308:53:19 2015-08-30
Analysis of relationships between pericytes and gas exchange capillaries in neonatal and mature bovine lungs - ir:ir-batch6-50838606:22:06 2015-09-03
Contractile elements in the regulation of macromolecular permeability - ir:ir-batch6-50633609:21:26 2015-09-04
Linking the basic sciences in teaching: suggestions for histology instruction - ir:ir-batch6-481333623:08:24 2015-08-31
Heterogeneity of the composition and thickness of tracheal mucus in rats - ir:ir-batch6-48531017:25:21 2015-09-03
The ultrastructure of nitzschia pungens f multiseries grun ex hasle - ir:ir-batch6-455135208:06:04 2015-09-04
Liver ultrastructure from the rat fed PCB 28. - ir:ir-batch6-480233318:22:19 2015-08-29
Limitations of monastral blue as a vascular label - ir:ir-batch6-49535701:32:13 2015-09-04
Recent advances in pericyte biology: implications for health and disease - ir:ir-batch6-49833801:33:40 2015-09-04
Non-aqueous fixative preserves macromolecules on the endothelial cell surface - ir:ir-batch6-49334514:51:25 2015-09-03
A role of pericytes in skeletal-muscle vasculature during macromolecular leakage - ir:ir-batch6-52133305:21:01 2015-09-04
Interleukin-2 alters the positions of capillary and venule pericytes in rat cremaster muscle - ir:ir-batch6-49129817:46:15 2015-09-01
Interleukin-10 inhibits interleukin-2-induced tumor necrosis factor production but does not reduce toxicity in C3H/HeN mice - ir:ir-batch6-48731101:31:55 2015-09-03
Morphometric analysis of pericyte-gas exchange capillary relationships in neonatal and mature bovine lungs - ir:ir-batch6-52338607:33:59 2015-09-02
The effect of soluble tumor necrosis factor receptor-II on endotoxin-mediated hemodynamic instability - ir:ir-batch6-49039317:23:18 2015-09-01
Ultrastructure of fibroblasts and pericytes in the parenchyma of neonatal and mature bovine lungs - ir:ir-batch6-52631120:48:07 2015-09-03
Orientation of adhering junctions between bovine pulmonary fibroblasts - ir:ir-batch6-50229723:47:55 2015-08-31
Pericytes and endothelial cell-junctions of bovine gas-exchange capillaries are concentrated where the blood-air barrier is thickest - ir:ir-batch6-52232918:03:50 2015-08-27
Microfilament-associated adhering junctions (6 nm F-maculae adherentes) connect bovine pulmonary fibroblasts in vivo - ir:ir-batch6-50928717:21:19 2015-09-03
Tumor necrosis factor causes microvascular protein leakage independently of neutrophils or mast cells - ir:ir-batch6-49229119:06:49 2015-09-02
N omega-nitro-L-arginine methyl ester inhibits inflammatory liver injury induced by interleukin-2 - ir:ir-batch6-48429523:14:35 2015-08-29
Differentiation of light-dye effects in the microcirculation - ir:ir-batch6-49630809:51:44 2015-09-01
Matrix metalloproteinase-2 (MMP-2) is present in the nucleus of cardiac myocytes and is capable of cleaving poly (ADP-ribose) polymerase (PARP) in vitro - ir:ir-batch6-48038523:05:13 2015-09-01
Neuro-epitheliomuscular cell and neuro-neuronal gap junctions in hydra - ir:ir-batch6-51035006:16:54 2015-09-03
Alteration of primate ovary surface epithelium by exposure to hexachlorobenzene - ir:ir-batch6-49934415:06:37 2015-08-31
Preservation of tracheal mucus by nonaqueous fixative - ir:ir-batch6-50332803:27:13 2015-09-02
Junctions connecting microfilament bundles between bovine pulmonary fibroblasts - ir:ir-batch6-52431612:06:45 2015-09-02
The pericyte: a review - ir:ir-batch6-50731501:46:59 2015-09-02
Comparative morphology of the scolices and microtriches among five species of Tetrabothrius (Eucestoda - ir:ir-batch6-48938108:36:03 2015-09-01
Interleukin 2 acutely induces platelet and neutrophil-endothelial adherence and macromolecular leakage - ir:ir-batch6-49731016:56:16 2015-09-03
Diversity within pericytes - ir:ir-batch6-48131309:23:19 2015-09-04
The first experience of livestock guarding dogs preventing large carnivore damages in Finland - ir:182044016:20:25 2015-09-03
Heterogeneity of pericyte populations in equine skeletal muscle and dermal microvessels - ir:350420215:56:34 2015-09-02
Adaptation of a fluorocarbon-based non-aqueous fixation regime for the ultrastructural study of the teleost epithelial mucous coat - ir:ir-batch6-48637401:04:00 2015-09-04
Uptake, disposition and depuration of domoic acid by blue mussels (Mytilus edulis) - ir:ir-batch6-352839709:41:08 2015-09-04
Distribution of Crenosoma vulpis and Eucoleus aerophilus in the lung of free-ranging red foxes (Vulpes vulpes) - ir:ir-batch6-328852816:53:49 2015-09-03
Skin morphology and humoral non-specific defence parameters of mucus and plasma in rainbow trout, coho and Atlantic salmon - ir:ir-batch6-20135621:25:20 2015-08-31
Invitro study of domoic acid uptake by digestive gland tissue of blue mussel (Mytilus-edulis-L) - ir:ir-batch6-52039800:05:13 2015-09-02
A comparative study of uptake and release of glutamic acid and kainic acid by blue mussel (Mytilus edulis L.) - ir:ir-batch6-352742721:14:24 2015-08-31
Effect of emu oil on auricular inflammation induced with croton oil in mice - ir:ir-batch6-48235513:04:38 2015-09-03
Morphology of the toxin-producing diatom Nitzschia-pungens Grunow forma multiseries Hasle - ir:ir-batch6-51937209:47:53 2015-09-04
In vitro study of domoic acid uptake by digestive gland tissue of blue mussel (Mytilus edulis L.) - ir:ir-batch6-352639211:13:35 2015-09-03
Morphometric assessment of epidermal and mucous-biofilm changes caused by exposure of trout to chloramine-T or formalin treatment - ir:ir-batch6-48334911:17:26 2015-09-03
Depuration of domoic acid from live blue mussels (Mytilus edulis ) - ir:ir-batch6-352536904:19:39 2015-09-03
Liver ultrastructure from the rat fed BCB 28. - ir:350724511:28:08 2015-08-28
Techniques for preservation of extracellular mucus - evaluation with the diatom Nitzschia pungens and rat tracheal epithelium - ir:ir-batch6-592544711:55:51 2015-09-02
The physiological response of Atlantic salmon, Salmo salar L., to a single experimental challenge with sea lice, Lepeophtheirus salmonis - ir:ir-batch6-18239600:32:20 2015-08-31
Estimation of total glomerular number using an integrated disector method in embryonic and postnatal kidneys - ir:897829723:10:43 2015-09-03
Susceptibility of rainbow trout Oncorhynchus mykiss, Atlantic salmon Salmo salar and coho salmon Oncorhynchus kisutch to experimental infection with sea lice Lepeophtheirus salmonis - ir:ir-batch6-21260911:28:54 2015-09-03
The transcription factor sry-related HMG box-4 (SOX4) is required for normal renal development in vivo - ir:658665323:10:45 2015-09-03
Physiological, biochemical, and histological approaches to examining sea lice-salmon interactions - ir:ir-batch6-506041819:08:27 2015-08-31