Electron microscopy for rapid identification of animal viruses in hematoxylin-eosin sections
Bhatnagar, R.Johnson, Gerald R.Christian, R. G.
Canadian Journal of Comparative Medicine
Pathology and Microbiology
Routine haematoxylin-eosin stained paraffin sections, were processed for electron microscopy, using a rapid method for localization of animal viruses. Formalin fixation was effective in preserving DNA as well as RNA viruses, however cellular fine structural details and organelles were not well preserved. The procedure is useful for morphological recognition of viral groups and as a rapid diagnostic aid for identifying viral disease..