microbicidal activity, mechanisms of action, and roles in innate immunity
Ramanathan, BalajiDavis, E. G.Ross, C. R.Blecha, F.
Microbes and Infection / Institut Pasteur
Antimicrobial peptides are important host-defense molecules of innate immunity. Cathelicidins are a diverse family of potent, rapidly acting and broadly effective antimicrobial peptides, which are produced by a variety of cells. This review examines the classification, antimicrobial spectrum, mechanism of action, and regulation of cathelicidins.