Biosynthetic studies of ecteinascidins in the marine tunicate Ecteinascidia turbinata

Kerr, Russell G.; Miranda, N. F.

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Kerr, R. G., & Miranda, N. F. (1995). Biosynthetic studies of ecteinascidins in the marine tunicate Ecteinascidia turbinata. Journal Of Natural Products, 58(10), 1618-1621.

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Title: Biosynthetic studies of ecteinascidins in the marine tunicate Ecteinascidia turbinata
Author(s): Kerr, Russell G.
Miranda, N. F.
Source: Journal of Natural Products
Genre: Journal Article
Date: 1995
Volume: 58
Issue: 10
Start Page: 1618
End Page: 1621
Department: Biomedical Sciences
Chemistry
Abstract: A viable cell-free extract of the marine tunicate Ecteinascidia turbinata has been generated that is capable of transforming amino acids into the ecteinascidin antitumor alkaloids. Tyrosine and cysteine were identified as two building blocks used in ecteinascidin production. The enzyme preparations in the in vitro studies were fortified with ATP, Mg super(2+), NADH, and NADPH.
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Biosynthetic studies of ecteinascidins in the marine tunicate Ecteinascidia turbinata

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