A novel biosynthetic route to pregnanes in the marine sponge Amphimedon compressa
Kerr, Russell G.Kelly, K.Schulman, A.
Journal of Natural Products
A novel degradative route to pregnanes has been elucidated in the marine sponge Araphimedon compressa. 22-Dehydrosterols, common in the diet of sponges, are the precursors to pregnanes and apparently are degraded by a mechanism analogous to the dealkylation of phytosterols to cholesterol.