Levamisole, morantel, fenbendazole, or ivermectin was administered at 2-week intervals from May 1 through Sept 14, 1985, to breeding ewes (20 ewes/drug) infected with various gastrointestinal nematodes. All ewes had fewer gastrointestinal nematode eggs per gram of feces (epg) after 2 treatments, com...

Efficacy of levamisole was evaluated in a suspected levamisole-resistant population of Haemonchus contortus in the Louisiana State University sheep flock. The efficacy of netobimin also was evaluated against this population of Haemonchus. In trial 1, 5 lambs naturally infected with H contortus were ...

A flock of 188 sheep was surveyed for cutaneous lesions that were noticed 3 days after shearing. On the basis of histologic features of the cyst wall, ie, association with sebaceous glands and lack of follicular structures or rete pegs, the cysts were classified as follicular cysts.

Testicular weight is a valuable measure of gonadal development in laboratory mice, but is usually only obtainable postmortem. The objective was to assess the utility of antemortem, noninvasive methods of predicting testicular weight and volume in peripubertal mice. Body weight, scrotal width, and ul...

A photo-activated sound alarm was placed in a specially designed sterile semi-conical sponge tampon and inserted into the vagina of the sow after labour had commenced, or on the day before expected parturition. When the tampon was expelled from the vagina by the first-born piglet and was thus expose...

After ischemic stroke, early thrombolytic therapy to reestablish tissue perfusion improves outcome but triggers a cascade of deleterious cellular and molecular events. Using a collaborative approach, our groups examined the effects of guanosine (Guo) in response to ischemic reperfusion injury in vit...

Substance P (SP) and cocaine employ similar mechanisms to modify excitatory synaptic transmission in the nucleus accumbens (NAc), a region implicated in substance abuse. Here we explored, using NAc slices, whether SP effects on these synaptic responses were altered in rats that have been sensitized ...

We tested the hypothesis that Substance P (SP) produces the same effects as cocaine by examining their actions on excitatory synaptic transmission in the nucleus accumbens (NAc). SP produced an irreversible depression of non-NMDA receptor mediated EPSC: EC50:0.12 uM; maximal suppression: −33.4 ± ...

The current investigation examined the role of estrogen in central autonomic regulatory nuclei on the autonomic dysfunction resulting from middle cerebral artery occlusion (MCAO). Experiments were done in anaesthetized male Sprague-Dawley rats. The effect of MCAO on autonomic tone was assessed by mo...

Thesis (Ph. D.)--University of Western Ontario, 1995. Includes bibliographical references.

There are currently four invasive tunicate species which are causing significant challenges to the aquaculture industry in Atlantic Canada: Ciona intestinalis, Styela clava, Botryllus schlosseri and Botrylloides violaceus. These tunicates foul mussel socks, aquaculture gear, boat hulls and wharves. ...

Microstimulation of the rat posterior insular cortex in phase with the ECG R wave elicits pure cardiac effects unaccompanied by changes in blood pressure or respiration. This technique has successfully demonstrated cardiac chronotropic organisation and arrhythmogenesis within the insula. Pathways ex...

The present study was aimed at investigating the efficacy and mechanism(s) of action of a Chinese herbal formulation, Liuwei Dihuang (LWDH), as a prospective natural weight-lowering product. Following a 2-week acclimation period, 48 obesity-prone (OP-CD) rats were divided into 4 groups (n=12 each). ...

Resistance development to parasiticides has been a problem in both terrestrial and aquatic environments. A major challenge exists in early detection of resistance emergence due to the low frequency at which resistant organisms can occur initially within a population and the difficulty in detecting t...

The zoonotic protozoan parasites Cryptosporidium parvum, and Giardia duodenalis can colonize the gastrointestinal tracts of many farmed, domestic and wild animals, and are capable of causing disease in humans. Due to their high prevalence in dairy and beef cattle, farms are considered to be potentia...

Many survivors of stroke experience arm impairments, which can severely impact their quality of life. Forcing use of the impaired arm appears to improve functional recovery in post-stroke hemiplegic patients, however the mechanisms underlying improved recovery remain unclear. Animal models of post-s...

Anophryoides haemophila is an important protistan parasite of American lobster, Homarus americanus, as it has been found to infect lobsters in the wild as well as causing major losses of lobsters maintained in commercial holding facilities. Expression of over 14,500 H. americanus hepatopancreatic ge...