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A brief description of the four types of hypersensitivity (Coombs and Gell 1968) is followed by a section on the release and pharmacology of anaphylaxis mediators and a description of laboratory models of anaphylactic shock, passive cutaneous anaphylaxis and of isolated tissue preparations used for ...
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Rev. of Veterinary Applied Pharmacology and Therapeutics, 5th ed., ed. by G.C. Brander, D.M. Pugh, R.J. Bywater, W.L. Jenkins
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Industrial depuration may provide a means of removing domoic acid toxin from blue mussels (Mytilus edulis ). Mussels containing up to 50 mu g domoic acid/g were transported from a Prince Edward Island estuary into controlled laboratory conditions to test the effects of temperature, salinity, mussel ...
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1. Pericytes are cells of microvessels (arterioles, capillaries and venules) that wrap around endothelial cells. They are most abundant on venules and are common on capillaries. 2. The pericyte population is highly variable between different tissues and organs, probably in a manner reflecting postar...
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The following experiments examine the role of estrogen as a central modulator of autonomic tone and baroreflex sensitivity in the female rat. Female Sprague-Dawley rats were ovariectomized and then supplemented daily for 7 days with a fixed dose of estrogen (5 microg/kg; sc) to produce a stable leve...
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Seven dogs with histories of intermittent vomiting and diarrhoea had greatly elevated alkaline phosphatase and alanine aminotransferase activities and total bilirubin concentrations. Exploratory laparotomy in each dog revealed a 3 to 10 cm mass in the body of the pancreas and obstruction of the comm...
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Acoustic telemetry showed that stomach temperature from large bluefin tuna, Thunnus thynnus, held in an impoundment, changed during feeding. The stomach cooled rapidly on ingesting cold food. It then warmed to a maximum of 10° to 15°C above water temperature over a period of 12 to 20 h. Temperatur...
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Many previous studies of obese rodents documented biochemical changes in pancreatic islets that contribute to hyperinsulinemia in vivo. Those studies used heterogeneous populations of islets, although the size of islets from obese rats ranges from 500 microm. Here, functional and morphological chang...
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This study combined bioassay-derived and direct chemical analysis of steroidal compounds in pulp and paper and municipal sewage effluent in order to determine the cause of masculinization of female mosquitofish. The bioassays used in this study consisted of androgen and estrogen receptor binding, an...
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Marfan syndrome, a connective tissue disorder affecting the cardiovascular system, is caused by mutations of fibrillin-based microfibrils. These mutations often affect the calcium-binding domains, resulting in structural changes to the proteins. It is hypothesized that these Ca+2 binding sites regul...
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This study is the first to examine the contractility of teleost ventricular muscle in an oscillating muscle preparation. The experiments were designed to test the relative importance of Ca2+ released from the sarcoplasmic reticulum (SR) and Ca2+ influx across the sarcolemma (SL) to cardiac performan...
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Examined whether cell proliferation in response to mitogens, natural killer cell (NK) activity, and macrophage functioning of mice may be influenced by either a neurogenic stressor (footshock) or psychogenic stressor (exposing the mouse to a predator, namely a rat).
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The safety of shellfish found and consumed in Nigeria is doubtful because no investigations have been carried out on their toxicity. The occurrence and toxicity of toxins in the commonly consumed Nigerian shellfish from Lagos, Warri, Oron, and Port Harcourt (PH) were investigated. Albino Wistar mice...
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As growth hormone transgenic Atlantic salmon consume more food to support their rapid growth, a study was conducted to determine if the morphology of the digestive tract would reflect these accelerated processes. Offspring from a non-transgenic cross that was spawned on the same day as the test fish...