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To secure the safety of international trade of animal and their derived products, it is required that animals should be proven infection-free using a validated diagnostic test certified by the World Organization for Animal Health (OIE). Test validation involves a multi-step evaluation process to as...
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There are currently four invasive tunicate species which are causing significant challenges to the aquaculture industry in Atlantic Canada: Ciona intestinalis, Styela clava, Botryllus schlosseri and Botrylloides violaceus. These tunicates foul mussel socks, aquaculture gear, boat hulls and wharves. ...
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Resistance development to parasiticides has been a problem in both terrestrial and aquatic environments. A major challenge exists in early detection of resistance emergence due to the low frequency at which resistant organisms can occur initially within a population and the difficulty in detecting t...
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There is limited scientific information on relationships among smallholder dairy group membership duration, sustainable livelihoods, food and nutrition security in developing countries, and whether nutrition education of women dairy farmers enhances the nutritional benefits of being a dairy group me...
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The objectives of this thesis were: 1) to determine which factors and biological samples were associated with the estimated amount of total arsenic (As) consumed from water and food; 2) to determine which factors were associated with the concentration of total and speciated As ([As]) in urine; 3) to...
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The Newfoundland and Labrador (NL) aquaculture industry is a major contributor of salmon products that help meet protein needs for the world’s growing population. The industry in NL continues to grow and evolve and now includes emerging species in its production such as Atlantic cod. In a growing ...
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The Atlantic Canadian aquaculture industry is dominated by Atlantic salmon production. In recent years, infectious disease, parasitic infestations, and price fluctuations from international competition have caused disruptions to the industry. Diversification of the industry away from Atlantic salmon...
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Syndromic surveillance is a tool for continuous, automated extraction of surveillance information from health data sources. The research documented in this dissertation aimed at exploring informatics and data mining tools in order to develop and implement techniques to harvest additional surveillanc...
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The purpose of this research was to evaluate herd and cow-level Mycobacterium avium subspecies paratuberculosis (MAP) diagnostic tests within non-infected and low to moderate within-herd prevalence MAP-infected herds. Specific objectives were to estimate herd-level sensitivity and specificity of env...
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Approximately 60% of human pathogens and emerging infectious diseases are zoonotic. Simulation models are increasingly being used to investigate the spread of diseases, evaluate intervention strategies and guide the decisions of policy makers. In this thesis a systematic review of modeling methods a...
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An in vitro comparison of the osteogenic potential of equine stem cell populations and subpopulations from multiple tissue sources was made to identify the ideal equine donor tissue as a source of MSCs to promote bone healing. Equine muscle tissue– and periosteal tissue–derived cells where chara...
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Measurement of systemic immunoglobulin (Ig) concentrations in horses and camelids is important for early and accurate diagnosis of immunodeficiencies in order to provide proper medical intervention. As a consequence, there is a demand for up-to-date, economic, rapid and precise diagnostic assays for...
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As an alternative to blanket dry cow therapy (BDCT), selective dry cow therapy (SDCT) is considered a more judicious approach to antimicrobial use for the purpose of mastitis control during the non-lactating period. The purpose of this research was to evaluate the utility of a 3M Petrifilm-based on-...
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One of the major limitations of the use of optoacoustics (OA) for the imaging of prostate cancer is the relatively low resolution when performed in real time. The work presented in this thesis aims to address this limitation by applying frequency-based analyses, which contribute additional informati...
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Shelters are potentially stressful environments for singly housed cats. The behaviour and faecal glucocorticoid metabolite (FGM) responses were examined in six shelter cats caged singularly for 30 days. Raised faecal glucocorticoid metabolite (FGM) concentrations and Cat-Stress-Scores (CSS) together...
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The focus of this research was to improve Mycobacterium avium subsp. paratuberculosis (MAP) control and management programs through increased understanding of the diagnostic detection ability of common pathogen and antibody assays over seasons and lactation stages, as well as through the novel use o...
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This thesis discusses and applies hierarchical models for survival data in the field of veterinary medicine. The focus is on hierarchical proportional hazards models when the baseline hazard is left completely unspecified. Parameter estimation for these models is explored and the performance of thei...
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In response to the global threats of emerging infectious diseases and bioterrorism events, public health surveillance developed analytical methods to cluster early health indicators from multiple data sources into “syndromes” for rapid and efficient disease detection. Syndromic surveillance has ...
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Modelling is a useful tool that has been applied in both human and animal epidemiological research. A model is a simplified system that represents a much more complex phenomenon. Various types of models are available. They are generally used for the purposes of explaining phenomena, making predictio...
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The welfare of horses transported for slaughter is a growing concern in several countries, including Canada, Iceland and the United States of America (USA). Slaughter of horses involves transportation of horses to a regulated facility and slaughter procedures such as lairage and stunning. The main o...
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In the early 1990s, the introduction of suspended culture methods and the development of a market for cocktail oysters (65–75 mm) propelled the oyster aquaculture industry in New Brunswick forward, now producing over 140,000,000 oysters (337,000 floating bags) on 2,649 hectares of private shellfis...