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Groups of Swiss white mice weighing 25-28 grams were infected orally with 500, 2,000, 5,000 or 20,000 oocysts of Eimeria falciformis var pragensis. Depression, anorexia, weight loss, diarrhea or dysentery, and dehydration were most pronounced at eight to ten days postinfection. The highest mortality...
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A computer-based fuzzy systems approach to diagnosis was compared with a standard rule-based approach for ability to diagnose 1 or more of 14 diseases in postpartum cows. A comparison between the 2 systems, using the same 12 input variables (clinical signs and laboratory measurements), resulted in 9...
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In order to test the hypothesis that treatment with glucocorticoids causes pancreatitis in dogs, 18 mongrel dogs were divided into three groups of six individuals, each group receiving prednisone at different doses orally or intramuscularly for two weeks. Two groups consisting of six dogs each serve...
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A trimethoprim-sulfonamide combination was administered to dogs for eight weeks at the therapeutic dose rate (15 mg/kg twice daily) and at three times the therapeutic dose rate (recommended maximum duration of therapy is two weeks). The lower dose produced no adverse effects, but the high dose cause...
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Intestinal function was assessed in cannulated loops of porcine proximal jejunum during immune-mediated emigration of neutrophils into the intestine. Net water, net sodium, net chloride, undirectional sodium and unidirectional chloride fluxes were measured before and after intestinal exposure to an ...
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Enterotoxigenic colibacillosis was experimentally produced in 8 of 9 colostrum-fed calves orally given 10(11) Escherichia coli. The eight calves developed profuse diarrhea accompanied by dehydration and depression. At 12 hours after exposure, all calves were euthanatized for necropsy and for collect...
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Mouse inoculation was used to test for the presence of a toxin in the serum, cerebrospinal fluid, and intestinal contents collected from cases of bovine enteric coccidiosis, with and without neurological signs, and from control calves. Intravenous inoculation of mice with 10 mL/kg of serum from calv...
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Intestinal loops, ligated in colostrum-deprived calves were used to compare the virulence of four isolates of bovine rotavirus. Histopathological studies were carried out on infected and control loops and measurements of villous length, crypt depth, villus:crypt ratio and crypt mitotic index were re...
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Two methods for detecting feline leukaemia virus (FeLV) antigen in peripheral blood were compared in 128 cats: immunofluorescence assay (IF) and an enzyme-linked immunosorbent assay (ELISA). Both healthy cats and cats with a variety of diseases, including lymphosarcoma and myeloproliferative disorde...
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The effects of oral and parenteral immunization on phagocytosis of enteropathogenic Escherichia coli by neutrophils in the intestinal lumen were studied in weanling pigs. Phagocytosis was assessed with the light and electron microscope on samples of fluid from ligated intestinal loops four hours aft...
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Glucocorticoid treatment in dogs is known to cause hepatocellular swelling due to accumulation of cytoplasmic compounds which variably have been identified histochemically as fat, glycogen, or water. In the present study changes in dog liver, after treatment for 15 days with two different doses of o...
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Athymic (nude) mice, their normal littermates, and Swiss white mice were infected with 750 oocysts of Eimeria falciformis var. pragensis and reinfected twice with 20,000 oocysts, 20 and 40 days after the primary infection. The prepatent and patent periods of the primary infection were similar in eac...
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In ligated intestinal loops of actively immunized adult mice, growth of V. cholerae 569B was suppressed approximately seven fold when compared to bacterial growth in non-immune animals. Similarly, growth of V. cholerae 569B was reduced in mice immunized with a hybrid vibrio strain, NCV569B-165, whic...
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This study was carried out to determine the diagnostic usefulness of postmortem eyefluid analysis in estimating antemortem concentrations of serochemical constituents. A total of 31 cattle, 18 dogs and 22 cats were selected from routine elective euthanasia submissions to a diagnostic laboratory. For...
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A malignant neoplastic process originating from gall bladder epithelium was diagnosed in a 14-year-old, spayed female, domestic shorthair cat. The tumor produced widespread pulmonary and lymphatic metastases. The clinical and pathological manifestations are described. Neoplasia arising from the gall...