Results

51 - 74 of 74
[Page generation failure. The bibliography processor requires a browser with Javascript enabled.]
Examined immune-deficiency markers, i.e., serum interleukin-6 (IL-6), IL-8, IL-6 receptor (IL-6R), IL-1R antagonist (IL1RA), gp130, and prostaglandin E2 (PGE2) production by mitogen-stimulated whole blood and the availability of plasma tryptophan in 10 patients with primary sleep disorders, 6 patien...
[Page generation failure. The bibliography processor requires a browser with Javascript enabled.]
It has been reported that activation of the inflammatory response system (IRS) may play a role in the aging process and in the pathogenesis of the degenerative changes associated with dementia of the Alzheimer type (DAT). This study examined the peripheral IRS in 31 normally aging Ss (age 22-91 yrs)...
[Page generation failure. The bibliography processor requires a browser with Javascript enabled.]
Recent evidence has suggested that an imbalance between membrane (n-3) and (n-6) fatty acids may contribute to the etiology of autoimmune and neurodegenerative diseases. In this study, the mechanisms by which eicosapentaenoic acid (EPA), gamma-linolenic acid (GLA), and arachidonic acid (AA) modulate...
[Page generation failure. The bibliography processor requires a browser with Javascript enabled.]
Evidence from clinical studies suggests that chronic exposure to physical and/or psychological stress profoundly affects the mental state and may be causally involved in anxiety and depressive disorders.
[Page generation failure. The bibliography processor requires a browser with Javascript enabled.]
There is some evidence that antipsychotic drugs may have immunosuppressive effects. This study examined the in-vitro effects of different concentrations of antipsychotic agents on cytokine production by human whole blood.
[Page generation failure. The bibliography processor requires a browser with Javascript enabled.]
Three common dosing regimens of the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced model of Parkinson's disease (PD) were compared in C57BL/6 mice on behavior, striatal and extra-striatal neurotransmission, and brain cytokines, to clarify the differences between regimens on these v...
[Page generation failure. The bibliography processor requires a browser with Javascript enabled.]
[Page generation failure. The bibliography processor requires a browser with Javascript enabled.]
[Page generation failure. The bibliography processor requires a browser with Javascript enabled.]
The effect of arginine vasopressin (AVP) on rat antinociception was investigated. Intraventricular injection of 50 or 100ng AVP dose-dependently increased the pain threshold; In contrast, intraventricular injection of 10mul anti-AVP serum decreased the threshold; both intrathecal injection of 200ng ...
[Page generation failure. The bibliography processor requires a browser with Javascript enabled.]
The olfactory bulbectomized (OB) rat has been developed as an animal model of depression. In the novel "open field" environment, male OB rats showed a hyperactivity which was attenuated by chronic treatment with desipramine (7.5 mg/ kg) for 20 days. Neutrophil phagocytosis was suppressed by the lesi...
[Page generation failure. The bibliography processor requires a browser with Javascript enabled.]
[Page generation failure. The bibliography processor requires a browser with Javascript enabled.]
This review attempts to critically assess the interplay between CRF, the immune and neurotransmitter systems, and behavior in chronic stress and depression.
[Page generation failure. The bibliography processor requires a browser with Javascript enabled.]
Macrophages produced proinflammatory cytokines and inflammatory responses can cause many symptoms of depression, including direct stimulation of the HPA axis and secretion of cortisol. In depressed patients, hypercortisolism has been well described as one of the major symptoms and also as the cause ...
[Page generation failure. The bibliography processor requires a browser with Javascript enabled.]
Variations of plasma ACTH and corticosterone, splenic macrophage activity, and mitogen-induced cell proliferation were determined in male rats following 15 min of either neurogenic stress (restraint) or psychogenic stress (exposure to a ferret). The effects of these stressors were assessed in 2 stra...
[Page generation failure. The bibliography processor requires a browser with Javascript enabled.]
Examined the serum concentration of corticosterone, neutrophil phagocytosis, lymphocyte proliferation, leucocyte adhesiveness/aggregation (LAA), and differential white blood cell (WBC) count in 50 male rats following exposure to the behavioral despair and open-field tests.
[Page generation failure. The bibliography processor requires a browser with Javascript enabled.]
[Page generation failure. The bibliography processor requires a browser with Javascript enabled.]
It has been demonstrated that the onset and progression of Alzheimer's disease (AD) are associated with inflammatory disorders in the brain. Although the interactions of inflammatory cytokines with neurotrophins have been reported in vitro, the balance change between inflammatory cytokines and ...
[Page generation failure. The bibliography processor requires a browser with Javascript enabled.]
[Page generation failure. The bibliography processor requires a browser with Javascript enabled.]
Examined whether cell proliferation in response to mitogens, natural killer cell (NK) activity, and macrophage functioning of mice may be influenced by either a neurogenic stressor (footshock) or psychogenic stressor (exposing the mouse to a predator, namely a rat).
[Page generation failure. The bibliography processor requires a browser with Javascript enabled.]
Eicosapentaenoic acid (EPA), a neuroactive omega-3 fatty acid, has been demonstrated to exert neuroprotective effects in experimental models of Parkinson's disease (PD), but the cellular mechanisms of protection are unknown. Here, we studied the effects of EPA in fully differentiated human SH-SY5Y c...
[Page generation failure. The bibliography processor requires a browser with Javascript enabled.]
Background: In Alzheimer's disease, stroke and brain injuries, activated microglia can release proinflammatory cytokines, such as interleukin (IL)-1β. These cytokines may change astrocyte and neurotrophin functions, which influences neuronal survival and induces apoptosis. However, the interaction ...
[Page generation failure. The bibliography processor requires a browser with Javascript enabled.]
Background In the last two decades, many studies have found that neuroinflammation is causally related to the onset [...] Background In Alzheimer?s disease, stroke and brain injuries, activated microglia can release proinflammatory cytokines, such as interleukin (IL)-1[beta]. These cytokines may cha...
[Page generation failure. The bibliography processor requires a browser with Javascript enabled.]
Eicosapentaenoic acid ( EPA), a neuroactive omega-3 fatty acid, has been demonstrated to exert neuroprotective effects in experimental models of Parkinson's disease ( PD), but the cellular mechanisms of protection are unknown. Here, we studied the effects of EPA in fully differentiated human SH-SY5Y...
[Page generation failure. The bibliography processor requires a browser with Javascript enabled.]
Eicosapentaenoic acid (EPA), a neuroactive omega-3 fatty acid, has been demonstrated to exert neuroprotective effects in experimental models of Parkinson's disease (PD), but the cellular mechanisms of protection are unknown. Here, we studied the effects of EPA in fully differentiated human SH-SY5Y c...