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There is considerable pressure for Animal Care and Ethics Councils to recommend using analgesics in experiments that involve fish. Although we do have some data regarding this issue, I argue that we do not know enough to recommend any being used. For example, the doses of morphine used in fish exper...
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Most athletes stretch as part of their training regimen and it is commonly believed that this practice prevents muscle injury. We tested this belief using an animal model, in situ mouse extensor digitorum longus (EDL) muscle. One lower hindlimb was slowly stretched for 1 min on alternate days for 12...
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Pain is a major sympton in many medical conditions, and often interferes significantly with a person's quality of life. Although a priority topic in medical research for many years, there are still few analgesic drugs approved for clinical use. One reason is the lack of appropriate animal model...
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To test predictions of biochemical symmorphosis, we measured the activity of seven consecutive glycolytic enzymes at three positions along the heterothermic white muscle of the bluefin tuna. Biochemical symmorphosis predicts that adjustments in sequential enzyme concentrations along a thermal gradie...
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The major fraction of elevated oxygen uptake of liver and skeletal muscle tissue slices that occurs during cold adaptation in mice is ouabain sensitive.
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Numerous environmental features have the potential to act as 'barriers' to fishes in the field. Passage of these 'barriers' depends on two main properties: willingness (behavioural) and physiological capacity. The physiological swimming capacity of fishes has been well studied. However, because most...
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Swimbladder walls of lake charr, Salvelinus namaycush, from Great Slave Lake (GSL), Northwest Territories, Canada, were unusually thick for the species. The thinnest sections of the GSL bladders (mean = 2.44mm, range = 1.1-4.4mm) were significantly thicker (P = 0.001) than lake charr swimbladders co...
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Acoustic telemetry showed that stomach temperature from large bluefin tuna, Thunnus thynnus, held in an impoundment, changed during feeding. The stomach cooled rapidly on ingesting cold food. It then warmed to a maximum of 10° to 15°C above water temperature over a period of 12 to 20 h. Temperatur...
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We examined the thermal biology of free-ranging terrestrial eastern foxsnakes (Elaphe gloydi Conant, 1940) that were voluntarily swimming in cold water during spring, in Georgian Bay, Ontario, Canada. Using temperature-sensitive radiotelemetry, we recorded body temperatures of foxsnakes during 12 co...
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We analyzed buoyancy characteristics ( buoyancy range, gas bladder volume, and lipid content) of adult bloater, Coregonus hoyi Gill, in the Laurentian Great Lakes. Buoyancy was measured directly in individual bloater and compared with the hydrostatic pressures at the depths of capture. The results o...
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Rainbow trout were exposed to sublethal waterborne Cd (5 and 10mugL(-1)) and dietary Ca (60mgg(-1)), individually and in combination, for 30d to elucidate the interactive effects and evaluate the toxicological significance of mitochondrial responses to these cations in vivo. Indices of fish conditio...
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We review studies claiming that fish feel pain and find deficiencies in the methods used for pain identification, particularly for distinguishing unconscious detection of injurious stimuli (nociception) from conscious pain. Results were also frequently misinterpreted and not replicable, so claims th...
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Objective - To assess the cardiorespiratory effects of morphine sulfate and evaluate whether morphine blocks cardiac responses to a noxious stimulus in winter flounder. Animals - 42 winter flounder (Pseudopleuronectes americanus) that were acclimated at 10°C. Procedures - Each fish was fitted with ...