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Autologous mesenchymal stem cells (MSCs) have been used as a potential cell-based therapy in various animal and human diseases. Their differentiation capacity makes them useful as a novel strategy in the treatment of tissue injury in which the healing process is compromised or delayed. In horses, bo...
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Both histidine-tryptophan-ketoglutarate (HTK) solution and Braile miniplegia are commercially available and used with high success. The objective of this work was to compare the effects of both strategies in an animal model. Twelve pigs were divided into control, HTK, or Braile groups using a model ...
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The aim of this study was to re-establish endocrine and reproductive function in tubal-ovariectomized rabbits using orthotopic tubal-ovary allo-transplants (OT-OA). Fifty-five New Zealand White nonconsanguineous rabbits were used and allocated into five experimental groups: Each group comprised dono...
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A sebaceous gland carcinoma was diagnosed in an adult African hedgehog (Atelerix albiventris). The neoplasm,was localized in the subcutis of the cervicall region and extendend towards the axilar region and along the thorax. The animal was admitted for surgical removal of the tumor but died during th...
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The multilobular tumor of bone (MTB) is considered as a slow-growth malignant tumor, which generally occurs on the cranium and facial bones of dogs, although it has been reported in other domestic animals. This study presents two cases of MTB in dogs. The first case was manifested in an 8-year-old m...
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Infertility has been considered a global public health problem in many countries worldwide. Our objective was to restore endocrine function and fertility in tubal-oophorectomized rabbits using an orthotopic tubal-ovarian vascularized autotransplant model as the anatomical-functional unit while emplo...
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The aim of this study was to define an experimental model in rabbits for subcutaneous heterotopic ovarian autotransplants and allotransplants in the inguinal region using a microvascular technique to restore endocrine function and ovulation. Forty sexually mature New Zealand white receptor rabbits a...
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The aim of this study was to establish a reverse transcription-polymerase chain reaction (RT-PCR) for the diagnosis of avian influenza virus in paraffin embedded tissues of experimentally infected animals, and to correlate viral detection by this method with the histological changes. Eight groups of...
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Recent advances in molecular biology have made possible the identification of genetic defects responsible for Wilson's disease, Indian childhood cirrhosis and copper toxicosis in Long Evans Cinnamon rats, toxic milk mice, and Bedlington terriers. The Wilson's disease gene is localized on h...
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This study evaluates the ability of selenium (Se) supplementation to prevent experimental copper (Cu)-induced hepatocellular damage. Weanling male Fischer 344 rats were randomly assigned to groups of 15, 3 groups (A,B,C) were fed Cu-loaded diets (containing 2000 microg/g copper, added as CuSO4) and ...
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OBJECTIVE: To determine the effects of chronic exposure to excess dietary copper (Cu) on liver specimens from rats and the effects of dietary selenium (Se) supplementation in experimental Cu toxicosis. ANIMALS: 60 weanling male Fischer 344 rats. PROCEDURE: Rats were randomly assigned to 4 groups of ...
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The aim of this study was to determine the amount of excess dietary copper (Cu) necessary to experimentally induce liver lesions characteristic of Cu-associated disease in Fischer 344 rats. Male weanling Fischer 344 rats of uniform age were divided into 6 groups (n = 5) and fed a rodent diet contain...
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OBJECTIVE: The aim of this study was to investigate the morphologic and biochemical effects of excess dietary copper in young and adult rats of different sex. METHODS: Adult Fischer 344 male and female rats were given a diet containing 1500 ppm copper for 18 weeks. Young male and female rats were fe...
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Parosteal osteosarcoma is a primary bone tumor on the osseous surface, and is typically composed by well differentiated but malignant fibrous, osseous and cartilaginous tissue. This tumor occurred in a male, 8 year old German Shepherd dog which was diagnosed by fine needle biopsy and X-rays and conf...
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The origin of different mesenchymal components which characterizes the canine mixed mammary tumours has been controversial since they were first described. Most of the authors have found, through different methods, important evidence that point out the myoepithelial cells as the responsibles ones. I...
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Cutaneous infections caused by Mycobacterium are rare in domestic animals in Mexico. The most affected species is the cat. The present case informs about a case of cutaneous mycobacteriosis in a dog describing its clinical and pathological findings. A similar case had never been reported in dogs unt...
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The spleen is the most common primary site for hemangiosarcoma in dogs. The tumor is characterized by rapid growth and widespread metastasis, presumably due to both its tissue of origin, the vascular endothelium, and its resultant ready access to systemic circulation. The most common clinical presen...
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A clinical and morphological description of a general nodular dermatofibrosis, associated to bilateral renal cystadenocarcinoma, is described. This case was found in a 10 year old Belgian Shepherd crossbred bitch. The animal presented multiple firm cutaneous nodules composed of dense well differenti...