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BACKGROUND: Cardiac disease has the potential to alter platelet function in dogs. Evaluation of platelet function using the PFA-100 analyzer in dogs of multiple breeds and with a broad range of cardiac conditions would help clarify the effect of cardiac disease on platelets. OBJECTIVES: The objectiv...

BACKGROUND: The platelet function analyzer (PFA)-100 is a point-of-care instrument previously evaluated in humans and dogs. In both species, artificially prolonged platelet closure time (CT) occurs with anemia. Reliability of the analyzer in dogs becomes a concern when the HCT is between 0.25 and 0....

Background A 10 week-old intact female German shepherd dog was examined because of a heart murmur.; Methods An echocardiogram revealed an extracardiac left-to-right shunt. An angiogram identified shunting between the aorta and the pulmonary artery in an unusual location.; Results Thoracotomy was per...

OBJECTIVE: To determine signalment, clinical signs, diagnostic findings, treatment, and outcome for cats with atrial fibrillation (AF). DESIGN: Retrospective study. ANIMALS: 50 cats. PROCEDURE: Medical records of cats that met criteria for a diagnosis of AF (ECG consisting of at least 2 leads, clear...

A 1 year old intact female Labrador retriever dog presented for evaluation of syncope caused by severe bradycardia. Advanced atrioventricular block was diagnosed. A mass infiltrating the interventricular septum and the tricuspid annulus was identified with echocardiography. Histopathological evaluat...

Blastomycosis was diagnosed in 6 dogs living in New York state. To our knowledge, blastomycosis has not been previously reported in dogs in this area, and maps that indicate the prevalence of blastomycosis in North America often partially or completely exclude the state of New York. Environmental ch...

OBJECTIVE: To assess the frequency of heart murmurs in overtly healthy cats. DESIGN: Prospective study. SAMPLE POPULATION: 103 healthy domestic cats. PROCEDURE: Background information and physical characteristics were assessed in cats that were candidates for blood donation during an 8-month period....

An 11-month-old, female Scottish terrier was presented with a history of a heart murmur. The electrocardiogram showed signs of left ventricular enlargement, and radiography confirmed generalized cardiomegaly. Echocardiography revealed four equally sized aortic valve cusps. A ventricular septal defec...

L-Carnitine is an amino acid derivative required for the beta -oxidation of long-chain fatty acids, a process necessary for deriving energy from fat. Carnitine deficiency has been shown to cause dilated cardiomyopathy in a small population of dogs, and effects of carnitine deficiency on other tissue...