Mast cells are crucial effector cells in host defense and immunoregulation. They are equipped with an impressive array of receptor systems which allows them to rapidly respond to pathogen-associated signals. G protein-coupled receptors (GPCRs) mediate mast cell activation and mediator release in res...
Proteomic and biochemical approaches to investigate the interactions between the Eastern Oyster, Crassostrea virginica and the MSX parasite, Haplosporidium nelsoni
The host parasite system of the MSX parasite, Haplosporidium nelsoni, in the eastern oyster, Crassostrea virginica, poses many challenges for experimental study. The interactions that are involved in the development of the typically high prevalence and intensities of disease encountered in certain e...