Twenty-three smooth fox terriers with an inherited form of myasthenia gravis were studied. All dogs developed muscle weakness between 4 and 8 weeks of age. This weakness increased in severity with exercise and age. Muscle weakness was alleviated by the administration of a short acting cholinesterase...

Clinical muscular and neurological signs are described for 13 Smooth Fox Terriers affected with a congenital form of myasthenia gravis. Treatment with a long-acting cholinesterase inhibitor in six cases resulted in temporary improvement in muscle strength. From examination of the phenotypes of 132 S...