A genetic mosaic analysis procedure in which Caenorhabditis elegans mosaics are generated by spontaneous loss of an extrachromosomal array is described. This technique allows almost any C. elegans gene that can be used in germline transformation experiments to be used in mosaic analysis experiments....

The genetic population structure of yellow perch Perca flavescens was assessed, with a focus on spawning groups within Lake Michigan. Six microsatellite DNA loci were evaluated, which had heterozygosities ranging from 0.21 to 0.86 in samples from seven Lake Michigan locations and six others in the n...

Traumatic detachment of the mitral valve from the annulus fibrosis occurred in a dog following blunt chest trauma. Euthanasia was elected approximately 7 months posttrauma due to refractory, chronic left heart failure. This is the first reported case of traumatic mitral valve rupture in a dog..

A microdissected pig genomic library was generated from the proximal half of the q arm of chromosome 6. Purified DNA was digested with restriction enzymes, ligated to oligonucleotide adaptors and amplified by PCR using primers complementary to the adaptor sequences. The purity of the amplified produ...

Calcinosis circumscripta associated with polydioxanone suture material was diagnosed in two young dogs. In each case, the owner noticed a firm mass at the site of a previous surgical incision. Mineralization of soft tissues was visible radiographically. At excision, multiple chalky white nodular mas...

Results demonstrated that xol-1 functions as an early developmental switch to set the choice of sexual fate and suggested that assessment of the X/A ratio occurs only early in embryogenesis to determine sex in Caenorhabditis elegans. Moreover, sdc-2, a gene that must be repressed by xol-1 to ensure ...

It has been shown previously that, in studies of hybrid populations there is a high probability of error in classifying individuals as parental, F1 or F2 on the basis of analysis of their genotypes. In the present work, the effects of the number of dominant loci examined on the probability of classi...

The results showed that mpk-1 plays an important functional role as an activator in ras-mediated cell signalling in vivo in C. elegans..

Medical records of 151 dogs with chronic hepatitis were reviewed. Corticosteroid treatment had a significant effect on improving survival time when corticosteroid-treated dogs were compared with untreated dogs. Dogs dying within 1 week of examination represented 37.1% of the cases, and when compared...

Coronaviruses were isolated from the mesenteric lymph nodes and intestinal washings from an adult cat with fatal enteritis, and from the lung, spleen and liver of an unrelated kitten that died at 4 days old. The comparative aspects of feline infectious peritonitis and feline panleukopenia are review...

The lin-31 gene is required for the proper specification of vulval cell fates in the nematode Caenorhabditis elegans and encodes a member of the winged-helix family of transcription factors. Members of this important family have been identified in many organisms and are known to bind specific DNA ta...

Fourier-transform infrared microscopic spectra of scrapie-infected nervous tissue measured at high spatial resolution (~6 micro m) were compared with those obtained from the purified, partly proteinase K digested scrapie isoform of the prion protein isolated from nervous tissue of hamsters infected ...

Deaths from acute zinc intoxication occurred among sheep that passed through a foot bath containing 20% zinc sulphate in order to obtain water. Experimentally it was shown that as little as 8 oz of a 20% zinc sulphate solution could kill within 4 hours of ingestion..

Effective population size (Ne) of a natural fish population was estimated from temporal changes in allele frequencies at 7 microsatellite loci. Analysis of an historical collection of fish scales increased the precision of estimates by increasing the time interval between samples and applying the re...

Clinical muscular and neurological signs are described for 13 Smooth Fox Terriers affected with a congenital form of myasthenia gravis. Treatment with a long-acting cholinesterase inhibitor in six cases resulted in temporary improvement in muscle strength. From examination of the phenotypes of 132 S...

The objective of this investigation was to determine the effects of varying levels of dietary protein on the postexercise increase in serum and muscle enzyme activity normally observed following exercise-induced muscle injury. Serum creatine kinase (CK), serum aspartate aminotransferase (AST), and m...

Autologous tissue transmission of spontaneously developing feline eosinophilic plaques was attempted in 5 cats. Macerated tissue from the plaque was vigorously rubbed onto 2 scarified skin sites in each cat. The inoculated areas were observed daily for 30 days. During that time, no clinical or histo...

Histopathological changes in the swim bladders of ciscos Coregonus artedii naturally infected with Cystidicola farionis included invasion of the subepithelium by histiocytic inflammatory cells, varying degrees of epithelial atrophy, and the occurrence of round granular cells in submucosal connective...

4 newborn calves from different herds were examined because of recumbency and inability to rise. Abnormal physical findings were confined to the nervous and/or musculoskeletal systems. The calves were necropsied, and histological findings included multifocal lymphocytic myelitis, meningitis, and enc...