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Bovine feedlots are intensive production systems of significant importance in Mexico, United States of America and Canada. Respiratory diseases are the single most important cause of morbidity and mortality in feedlot cattle. Herein, the gross and microscopic findings in the lungs of cattle with unu...
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OBJECTIVE: To evaluate the effect of 2 oxytocin products administered to sows at the onset of fetal expulsion on the integrity of umbilical cords, meconium staining, and piglet mortality. ANIMALS: 2099 neonatal pigs. PROCEDURE: 180 parturient sows were randomly assigned to 3 stratified groups of 60 ...
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This study was designed to test whether intraperitoneally injected sodium hydrosulfide (NaHS) would mimic the pulmonary alterations induced by lethal peracute exposure to an atmosphere containing hydrogen sulfide. Groups of five Sprague-Dawley rats were exposed to an atmosphere of either 2317.6 +/- ...
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A method used to calculate the number of P. haemolytica reaching the lungs of calves during an aerosol exposure is described. This method is based on a linear relationship of bacterial deposition in lungs of mice and calves when exposed to the same bacterial aerosol.
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Based on current literature which commonly associates bovine virus diarrhea virus and M. bovis with pneumonic pasteurellosis, an investigation was conducted into the effect of these 2 pathogens on the capacity of bovine lung to clear inhaled P. haemolytica. There was no significant effect (P > 0....
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Ultrastructural and morphometric profiles of type-II pneumocytes (P-II) were investigated in rats killed 18 or 24 hours after a single intratracheal inoculation of bacterial (Escherichia coli) lipopolysaccharide (LPS). Inoculation with LPS induced pulmonary injury and inflammation, as measured by in...
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This study was conducted to investigate the in vivo effect of a single intratracheal inoculation of Pasteurella haemolytica cytotoxin on the rat lung. Changes in the biochemical and cytological composition of bronchoalveolar lavage fluid were used to estimate the magnitude of pulmonary cell injury, ...
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This study was conducted to investigate the effect of sex, age, number of bronchoalveolar lavages and method of quantitation on the number of bronchoalveolar cells in rats. Forty Long Evans rats were divided into four age-sex subgroups of ten animals each. Nine consecutive bronchoalveolar lavages we...
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Since toxicity studies among different laboratories generally involve rats of different sex and age, this study was conducted to investigate the effect of sex, age and animal to animal variation in the activities of lactate dehydrogenase and alkaline phosphatase from bronchoalveolar lavage fluid, br...
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The relationship between acute pulmonary cell injury and inflammatory response was investigated in rats killed 1, 3, and 7 days after intratracheal inoculation with bacterial lipopolysaccharide (LPS). Activities of lactate dehydrogenase (LDH) and alkaline phosphatase (AP) in bronchoalveolar lavage (...
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A 4-year-old, male Newfoundland cross was presented for lethargy, anorexia, and dysuria. The main clinical finding was an enlarged and painful prostate gland. While the dog was hospitalized, priapism developed. Following euthanasia, microscopic examination revealed that a carcinoma involving both bl...
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Concentration-time interactions were investigated in young male and female Sprague-Dawley, Long Evans and Fischer-344 rats exposed to hydrogen sulphide for two,four or six hours. Higher concentrations caused more deaths, with no significant difference for duration of exposure. A significant sex effe...
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The design of and the analysis of data from the Bruce County Beef Cattle Project, particularly the field study, are presented and discussed. A major value of the study may lie in its ability to relate laboratory findings to events in the field. The factor most strongly related to mortality was ratio...