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Cranberry (Vaccinium macrocarpon) flavonoids inhibit matrix metalloproteinases (MMPs) in human prostate cancer cells
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Blueberry (Vaccinium angustifolium) flavonoid-containing fractions have been shown to inhibit MMP activity (MMP-2/-9) in DU145 prostate cancer cells. This study examined the effect of a whole cranberry extract on MMP activity in DU145 cells. MMP-2/-9 activity was inhibited by this cranberry extract ...
IGF-1 and IGF-2 mediated expression and regulation of ornithine decarboxylase and spermidine
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Altered expression
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Lipopolysaccharide, cranberry flavonoids, and regulation of ornithine decarboxylase [ODC] and spermidine
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Sensitivity of Erwinia spp. to salt compounds in vitro and their effect on the development of soft rot in potato tubers in storage
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Several salt compounds were tested in vitro as inhibitors of Erwinia carotovora subsp. atroseptica (van Hall) Dye (Eca) and Erwinia carotovora subsp. carotovora (Jones) Bergey, Harrison, Breed, Hammer & Huntoon (Ecc), causal agents of bacterial soft rot of potato. All compounds were mixed with p...
Effect of salt compounds on mycelial growth, sporulation and spore germination of various potato pathogens
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Oncostatin M-mediated regulation of matrix metalloproteinases and associated mediators of MMPs' expression in H-ras transformed fibroblasts
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Oncostatin M (OSM) is a growth and differentiation factor which has been shown to exert both stimulatory and inhibitory effects on tissue invasion in various cell lines. Tissue invasion is a key marker of metastases and can be monitored by examining activities associated with ECM degradation such as...
Regulation of ornithine decarboxylase (ODC) and spermidine
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Phorbol-12-myristate acetate [PMA] mediated regulation of spermidine/spermine N-1 acetyltransferase expression in H-ras transformed fibroblasts
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Over-expression of K-FGF or bFGF results in altered expression of matrix metalloproteinases
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Matrix metalloproteinase (MMP) expression was investigated in NIH-3T3 fibroblasts that secrete K-FGF and in NIH-3T3 cells which express chimeric bFGF with a signal sequence targeting bFGF to the secretory pathway. Correlations between altered MMPs' and other proteases' expression and malig...