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Milbemycin oxime was used to treat dogs with natural infections of the fox lungworm, Crenosoma vulpis and the French heartworm, Angiostrongylus vasorum. Crenosomosis was identified in 42 of 202 dogs with clinical signs of coughing, dyspnoea or exercise intolerance by a Baermann analysis of faecal sa...
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Between August 1992 and November 1995, 31 moribund or dead common loons (Gavia immer) found in the three Maritime provinces of Canada (New Brunswick, Nova Scotia, Prince Edward Island) were necropsied. Eight of these birds were in good body condition and died acutely from drowning or trauma. The rem...
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The long-term (i.e., 4-5 months) effects of large doses (3 X 50 mg/kg) of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on striatal dopamine-containing afferents were studied in the NMRI strain of mice. Recently improved in vivo electrochemical methods were first used to examine the magnitude,...
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Described are the first antemortem diagnosis made via fecal examination using the Baermann technique and the first postmortem recovery of endemic Angiostrongylus vasorum in dogs from North America, specifically the Avalon peninsula of Newfoundland. In one dog, A. vasorum was recovered and identified...
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Life-span and reproductive capacity of sea lice, Lepeophtheirus salmonis, were investigated in artificial seawater (Instant OceanReg.) under laboratory conditions. Sea lice were maintained on Atlantic salmon (Salmo salar) in recirculation systems for as long as 7 months. During this period sea lice ...
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Experiments involving 200 rainbow trout showed that host defence mechanisms in sea lice-infested fish are impaired, predisposing fish to subsequent infections to a second pathogen, such as the microsporidian parasite Loma salmonae. Macrophage impairment in lice-infested fish occurred when sea lice b...
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A young, female llama (Lama glama) was euthanized following the onset of hindleg paresis and paralysis. Live trematodes, identified as Fascioloides magna, were identified from the liver of this animal. This represents the first report of F. magna in a llama.
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Angiostrongylus vasorum, French Heartworm, is a metastrongylid nematode infecting the pulmonary arteries and right heart of wild and domestic canids in various regions of the world. Infection in dogs can result in fatal cardiopulmonary disease. A single endemic focus of A. vasorum in North America o...
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The effects of Lepeophtheirus salmonis, on non-specific defence mechanisms in Salmo salar, were determined by experimentally infesting 180 hatchery-reared post-smolts with laboratory-grown infective copepodids at moderate to high infection intensities ranging from 15 to 285 lice per fish. The effect...
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Monthly bulk-tank milk samples were obtained from 415 Nova Scotia dairy herds in each of the months of July-September 1998 and tested using an indirect microtitre ELISA against a crude saline-extract, whole-worm Ostertagia ostertagi antigen. ELISA results (optical densities (ODs)) were consistent ac...
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The guinea pig was used to study the pathology of Fascioloides magna, an important pathogen for sheep. Although flukes migrated freely through various tissues in infected guinea pigs, the most serious lesions occurred in the liver and lungs. The sequential development of lesions indicated that fluke...
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Crenosoma vulpis is a nematode lungworm that is highly prevalent in the red fox population of Atlantic Canada. Dogs are susceptible to infection with clinical signs consisting primarily of a chronic cough. A recent report of C. vulpis infection in 3 dogs on Prince Edward Island prompted an investiga...
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Larvae of Trichinella sp. were found in two of 208 red foxes (Vulpes vulpes) and one of 125 coyotes (Canis latrans) obtained from trappers from Prince Edward Island (Canada) in 1995 and 1996. A polymerase chain reaction based DNA biotyping method revealed the larvae to be isolates of Trichinella spi...
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The efficacy of closantel against experimentally induced Fascioloides magna infection in sheep was studied. In each of 3 experiments, closantel was administered 8 weeks after the sheep were given (oral inoculation) 100 metacercariae of F magna. In the 1st experiment, closantel was given orally to 5 ...