Conduction block in one-dimensional heart fibers

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Citation

Title Conduction block in one-dimensional heart fibers
Author(s) J. Fox, R. Gilmour, E. Bodenschatz
Journal Physical Review Letters
Date 2002
Volume 89
Issue 19
Start page 198101
End page 198101
Abstract We present a nonlinear dynamical systems analysis of the transition to conduction block in one-dimensional cardiac fibers. We study a simple model of wave propagation in heart tissue that depends only on the recovery of action potential duration and conduction velocity. If the recovery function has slope >or=1 and the velocity recovery function is nonconstant, rapid activation causes dynamical heterogeneity and finally conduction block away from the activation site. This dynamical mechanism may play a role in the initiation and breakup of spiral waves in excitable media.
ISSN 0031-9007
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