Transport of palmitic acid across the tegument of ...



Title Transport of palmitic acid across the tegument of the entomophilic nematode Romanomermis culicivorax
Author(s) R. Gordon, I. R. Burford
Journal Journal of Nematology
Date 1984
Volume 16
Issue 1
Start page 14
End page 21
Abstract R. culicivorax larvae, dissected out of Aedes aegypti larvae 7 days after infection, were incubated under controlled conditions in isotonic saline containing 14C-U-palmitic acid to investigate the nature of the transport mechanism(s) used by the nematode for transcuticular uptake of palmitic acid. Net uptake of the isotope by the nematode was of a logarithmic nature with respect to time. Uptake of palmitic acid was accomplished by a combination of diffusion and a mediated process which was substrate saturable and competitively inhibited by myristic and stearic acids. Both 2,4-dinitrophenol and ouabain inhibited uptake of palmitic acid and thus supported the hypothesis that the carrier system is of the active transport variety and is coupled to a Na+K+ ATPase pump..

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