Cardiovascular effects and fatalities associated ...

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Title Cardiovascular effects and fatalities associated with intravenous administration of doxycycline to horses and ponies
Author(s) J. L. Riond, J. E. Riviere, Wendy M. Duckett, C. E. Atkins, A. D. Jernigan, Y. Rikihisa, S. L. Spurlock
Journal Equine Veterinary Journal
Date 1992
Volume 24
Issue 1
Start page 41
End page 45
Abstract Intravenous use of doxycycline in horses is associated with deleterious side effects on the cardiovascular system which may result in fatalities. At dosages and infusion rates used in these studies, supraventricular tachycardia, systemic arterial hypertension, clinical signs of discomfort, collapse and death were observed. Results of the present study suggest that the intravenous use of doxycycline should be avoided in horses.

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