Effect of volume variations on osteogenic ...
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| Title | Effect of volume variations on osteogenic capabilities of autogenous cancellous bone graft in dogs |
| Author(s) | W. DeVries, C. Runyon, S. Martinez, W. Ireland |
| Journal | American Journal of Veterinary Research |
| Date | 1996 |
| Volume | 57 |
| Issue | 10 |
| Start page | 1501 |
| End page | 1505 |
| Abstract | OBJECTIVE: To evaluate the osteogenic effect of differing volumes of autogenous cancellous bone graft (ACBG) placed into partial cortical defects of the ulna. ANIMALS: 15 healthy, mature Beagles. PROCEDURE: Weekly radiographic views of defects were obtained over 8 weeks and were analyzed for bone density by use of radiographic optical densitometry. Histologic sections were obtained 8 weeks after surgery and were planimetrically evaluated for area of total, lamellar, and woven bone. RESULTS: Defects receiving 0.3 and 0.75 g of ACBG had rapid initial bone production, and dogs receiving 0.3 g of ACBG had faster bone ingrowth than did those receiving 0.1 g of ACBG or controls. Defects receiving 0.75 g of ACBG had a rate of bony ingrowth equal to 0.3 g of ACBG. There was no difference in the histomorphometric area fractions of total, lamellar, or woven bone between defects treated with 0.1 or 0.75 g of ACBG, and between grafted or control defects, 8 weeks after surgery. CONCLUSIONS: Overfilling a cortical defect with ACBG does not enhance early osteogenesis within the defect, and underfilling will delay the onset of osteogenesis within the defect. CLINICAL RELEVANCE: A volume of ACBG sufficient only to fill a cortical defect is required to obtain a clinical osteogenic effect from the graft. |
| ISSN | 0002-9645 |
| Use/Reproduction | Contact Author |
Using APA 6th Edition citation style.
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