Deficient cutaneous response to PHA-P in healthy ...

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Title Deficient cutaneous response to PHA-P in healthy puppies from a kennel with a high prevalence of demodicosis
Author(s) B. N. Wilkie, R. J. Frederick Markham, C. Hazlett
Journal Canadian Journal of Comparative Medicine. Revue Canadienne de Medecine Comparee
Date 1979
Volume 43
Issue 4
Start page 415
End page 419
Abstract Intradermal injection of phytohemagglutinin was used to evaluate the integrity of cell-mediated immunological reactions in Doberman puppies thought to be predisposed to demodicosis. Results indicate a statistically significant deficiency of cutaneous delayed response in these dogs when compared with age matched Beagles, adult Dobermans or random control dogs of various ages and breeding. The high prevalence of demodicosis in the kennel of origin may have been due to the observed deficiency of cutaneous immune function.

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