Local adjuvants: the influence of sodium ...



Title Local adjuvants: the influence of sodium dodecylbenzene sulphonate on immunization with aerosolized antigen
Author(s) R. J. Frederick Markham, B. N. Wilkie
Journal Experientia
Date 1979
Volume 35
Issue 3
Start page 414
End page 416
Abstract Guinea-pig respiratory and serum antibody responses were enhanced following exposure to aerosols of bovine IgG2 dissolved in solutions of sodium dodecylbenzene sulphate (SDBS). Enhanced response was seen in both primary and secondary immunization. Cell-mediated immune response (indirect macrophage migration influencing test) was not altered by SDBS. Results are discussed with a view to the possible utility of SDBS as adjuvant for prophylactic immunization.

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