Histological observations on precystic merogony and ...

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Title Histological observations on precystic merogony and metrocyte formation of Sarcocystis rauschorum (Apicomplexa: Sarcocystidae) in varying lemmings, Dicrostonyx richardsoni
Author(s) Richard J. Cawthorn, R. J. Brooks
Journal Canadian Journal of Zoology
Date 1985
Volume 63
Issue 12
Start page 2907
End page 2912
Abstract The early endogenous development of S. rauschorum in D. richardsoni was studied. After determining the dose-response effects of sporocysts of S. rauschorum on lemmings (doses greater than 500 sporocysts were lethal during hepatic merogony), sporocysts were administered to additional lemmings that were killed beginning one day postinoculation (DPI) and continuing to 15.0 DPI. Merogony of S. rauschorum occurs in hepatocytes 4-6 DPI: merozoites were also found in leukocytes 5-6 DPI in liver impression smears. Cyst formation began 9.0 DPI in striated muscle (rarely in cardiac muscle) and early metrocytes were present to 15.0 DPI. Overall, S. rauschorum has only one precystic generation of merogony, in hepatocytes, and then rapidly forms cysts containing metrocytes in striated musculature..

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